Evidence map›Paper›PMID 33443651›Full record

ArticleCell biochemistry and biophysics2021

Morphometry and Modeling of Label-Free Human Melanocytes and Melanoma Cells.

Sharareh Tavaddod, Behnaz Shojaedin-Givi, Mahnaz Mahmoudi-Rad, Hossein Naderi-Manesh

Abstract read
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In one paragraph

Article in Cell biochemistry and biophysics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sharareh Tavaddod *School of Physics and Astronomy, University of Edinburgh, Edinburgh, UK. stavaddod@ed.ac.uk.
Behnaz Shojaedin-Givi *Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Mahnaz Mahmoudi-RadSkin Research Center, Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran.
Hossein Naderi-ManeshDepartment of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran. naderman@modares.ac.ir.ORCID http://orcid.org/0000-0002-4227-171X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A combination of light microscopy and image processing was applied to investigate morphology of label-free primary-melanocytes and melanoma cells. A novel methodological approach based on morphology of nuclear body was used to find those single cells, which were at the same phase of cell cycle. The area and perimeter of melanocytes and melanoma cells were quantified. We found that there was a significant difference between area and perimeter of adendritic-shaped melanocytes with melanoma cells and the reason(s) of this finding was speculated. Finally, a theoretical model based on losing dendrites was proposed, which was in agreement with our experimental data.

Indexed as

Cells, CulturedCell ShapeG1 PhaseHumansImage Processing, Computer-AssistedMelanocytesMelanomaMicroscopyCell shapeImage processingMelanocyteMelanomaMorphometry

Identifiers

PMID33443651

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.