Evidence map›Paper›PMID 33443534›Full record

ReviewBioscience reports2021

The role of EMT-related lncRNA in the process of triple-negative breast cancer metastasis.

Haomeng Zhang, Jiao Wang, Yulong Yin, Qingjie Meng, Yonggang Lyu

Abstract readReview
In one paragraph

Review in Bioscience reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Mechanistic insights into the lncRNA-Notch signaling axis in tumors.Frontiers in cell and developmental biology · 2026
    Review
  3. The Role of the Fox Gene in Breast Cancer Progression.International journal of molecular sciences · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. FRA-1 as a Regulator of EMT and Metastasis in Breast Cancer.International journal of molecular sciences · 2023
    Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haomeng ZhangDepartment of Thyroid and Breast Surgery, Xi'an No. 3 Hospital, The Affiliated Hospital of Northwest University, Fengcheng 3rd Road 10, Weiyang District, Xi'an, Shaanxi 710018, P. R. China.
Jiao WangDepartment of Radiotherapy, The First Affiliated Hospital of Xi'an Jiaotong University, Yanta West Road 277, Yanta District, Xi'an, Shaanxi 710061, P. R. China.
Yulong YinDepartment of Thyroid and Breast Surgery, Xi'an No. 3 Hospital, The Affiliated Hospital of Northwest University, Fengcheng 3rd Road 10, Weiyang District, Xi'an, Shaanxi 710018, P. R. China.
Qingjie MengDepartment of Thyroid and Breast Surgery, Xi'an No. 3 Hospital, The Affiliated Hospital of Northwest University, Fengcheng 3rd Road 10, Weiyang District, Xi'an, Shaanxi 710018, P. R. China.
Yonggang LyuDepartment of Thyroid and Breast Surgery, Xi'an No. 3 Hospital, The Affiliated Hospital of Northwest University, Fengcheng 3rd Road 10, Weiyang District, Xi'an, Shaanxi 710018, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is the most malignant and fatal subtype of breast cancer, which has characterized by negativity expression of ER, PR, and HER2. Metastasis is the main factor affecting the prognosis of TNBC, and the process of metastasis is related to abnormal activation of epithelial-mesenchymal transition (EMT). Recent studies have shown that long non-coding RNA (LncRNA) plays an important role in regulating the metastasis and invasion of TNBC. Therefore, based on the metastasis-related EMT signaling pathway, great efforts have confirmed that LncRNA is involved in the molecular mechanism of TNBC metastasis, which will provide new strategies to improve the treatment and prognosis of TNBC. In this review, we summarized many signal pathways related to EMT involved in the transfer process. The advances from the most recent studies of lncRNAs in the EMT-related signal pathways of TNBC metastasis. We also discussed the clinical research, application, and challenges of LncRNA in TNBC.

Indexed as

Epithelial-Mesenchymal TransitionHumansNeoplasm MetastasisRNA, Long NoncodingTriple Negative Breast NeoplasmsRNA, Long NoncodingEpithelial-mesenchymal transition(EMT)long non-coding RNA(LncRNA)MetastasisTriple-negative breast cancer(TNBC)

Identifiers

PMID33443534
PMCPMC7859322

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.