Evidence map›Paper›PMID 33443453›Full record

Trial reportClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Long-Term Safety and Efficacy of Antiplatelet Therapy in Patients With Cerebral Infarction With Thrombocytopenia.

Shijie Guo, Yingying Lin, Xiaoye Ma, Yanxin Zhao, Aiping Jin, Xueyuan Liu, Letao Sun, Guilin Meng

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Safety of early antiplatelet therapy for non-cardioembolic mild stroke patients with thrombocytopenia.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Shijie GuoDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yingying LinDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Xiaoye MaDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yanxin ZhaoDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Aiping JinDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Xueyuan LiuDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Letao SunGordon F. Derner School of Psychology General Psychology, Adelphi University, New York, United States.
Guilin MengDepartment of Neurology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0001-8168-7569
Tongji University · CNAdelphi University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the long-term safety and benefits of antiplatelet therapy in patients with cerebral infarction with thrombocytopenia, as evidence regarding this was limited. This cohort trial assessed patients with acute cerebral infarction with thrombocytopenia treated in the Neurology Department of Shanghai Tenth People's Hospital from January 2016 to December 2018, and enrolled patients were followed up for 9 months. The patients were divided into non-antiplatelet and antiplatelet groups based on the actual intake of antiplatelet drugs. Primary endpoints included hemorrhagic events, recurrence of cerebral infarction, and activity of daily living (ADL) score changes. To balance baseline clinical data, propensity score matching was applied, and there were finally 65 matched patients, including 30 and 35 in the antiplatelet and non-antiplatelet groups, respectively. There were no differences in hemorrhagic and cerebral infarction recurrence rates between the 2 groups. ADL score change was higher in the antiplatelet group than in the non-antiplatelet group (10 vs 5,

Indexed as

Activities of Daily LivingAgedAged, 80 and overAspirinCerebral InfarctionChinaClopidogrelCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedOutcome Assessment, Health CarePlatelet Aggregation InhibitorsPropensity ScoreAspirinClopidogrelPlatelet Aggregation Inhibitorsantiplatelet therapycerebral infarctionefficacysafetythrombocytopenia

Identifiers

PMID33443453
PMCPMC7812396
OpenAlexW3119974373

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.