Evidence map›Paper›PMID 33443213›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Maternal GABAergic and GnRH/corazonin pathway modulates egg diapause phenotype of the silkworm

Ryoma Tsuchiya, Aino Kaneshima, Masakazu Kobayashi, Maki Yamazaki, Yoko Takasu, Hideki Sezutsu, Yoshiaki Tanaka, Akira Mizoguchi, Kunihiro Shiomi

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 70 citations in OpenAlex.

  1. Targeting the circadian negative regulatorMaterials today. Bio · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Insects · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Circadian Clock GeneBiology · 2021
    Article
  15. GnRH-Related Neurohormones in the Fruit FlyInternational journal of molecular sciences · 2021
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ryoma TsuchiyaFaculty of Textile Science and Technology, Shinshu University, Ueda 386-8567, Japan.
Aino KaneshimaFaculty of Textile Science and Technology, Shinshu University, Ueda 386-8567, Japan.
Masakazu KobayashiFaculty of Textile Science and Technology, Shinshu University, Ueda 386-8567, Japan.
Maki YamazakiFaculty of Textile Science and Technology, Shinshu University, Ueda 386-8567, Japan.
Yoko TakasuNational Agriculture and Food Research Organization, 305-8634 Tsukuba, Japan.ORCID 0000-0003-4539-769X
Hideki SezutsuNational Agriculture and Food Research Organization, 305-8634 Tsukuba, Japan.
Yoshiaki TanakaNational Agriculture and Food Research Organization, 305-8634 Tsukuba, Japan.
Akira MizoguchiDivision of Liberal Arts and Sciences, Aichi Gakuin University, Nisshin 470-0195, Japan.
Kunihiro ShiomiFaculty of Textile Science and Technology, Shinshu University, Ueda 386-8567, Japan; shiomi@shinshu-u.ac.jp.ORCID 0000-0002-0140-5769
Shinshu University · JPNational Agriculture and Food Research Organization · JPAichi Gakuin University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diapause represents a major developmental switch in insects and is a seasonal adaptation that evolved as a specific subtype of dormancy in most insect species to ensure survival under unfavorable environmental conditions and synchronize populations. However, the hierarchical relationship of the molecular mechanisms involved in the perception of environmental signals to integration in morphological, physiological, behavioral, and reproductive responses remains unclear. In the bivoltine strain of the silkworm

Indexed as

Amino Acid SequenceAnimalsBombyxCell MembraneDiapauseEmbryonic DevelopmentGABA-A Receptor AntagonistsGABAergic NeuronsGABA Plasma Membrane Transport Proteinsgamma-Aminobutyric AcidInsect ProteinsNeuropeptidesOvumPhylogenyReceptors, GABA-ASignal Transductioncorazonin protein, insectdiapause hormoneGABA-A Receptor AntagonistsGABA Plasma Membrane Transport Proteinsgamma-Aminobutyric AcidInsect ProteinsNeuropeptidesReceptors, GABA-ABombyx moricorazonindiapause hormoneGABAGABA transporter

Identifiers

PMID33443213
PMCPMC7817158
OpenAlexW3114618450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.