Evidence map›Paper›PMID 33443212›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Efficient CRISPR-mediated base editing in

Savio D Rodrigues, Mansour Karimi, Lennert Impens, Els Van Lerberge, Griet Coussens, Stijn Aesaert, Debbie Rombaut, Dominique Holtappels, Heba M M Ibrahim, Marc Van Montagu and 4 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Engineering Agrobacterium for improved plant transformation.The Plant journal : for cell and molecular biology · 2025
    Review
  5. Review
  6. Article
  7. Precision engineering of the probioticApplied and environmental microbiology · 2025
    Article
  8. IMAGE: INTEGRATE-MediatedFrontiers in microbiology · 2025
    Article
  9. Genomic engineering inFrontiers in microbiology · 2025
    Article
  10. Article
  11. Article
  12. NovelMicroorganisms · 2024
    Article
  13. Article
  14. Article
  15. Recent Advances in Tomato Gene Editing.International journal of molecular sciences · 2024
    Review
  16. EnhancingFrontiers in plant science · 2024
    Article
  17. Review
  18. Review
  19. Article
  20. Complete genome sequence ofMicrobiology resource announcements · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Savio D RodriguesDivision of Crop Biotechnics, Department of Biosystems, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0003-1641-6310
Mansour KarimiDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0002-0246-9318
Lennert ImpensDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0002-6330-4744
Els Van LerbergeDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0002-8407-7413
Griet CoussensDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0003-2285-5782
Stijn AesaertDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0001-8787-7347
Debbie RombautDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.
Dominique HoltappelsLaboratory of Gene Technology, Department of Biosystems, Division Animal and Human Health Engineering, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0003-4263-3407
Heba M M IbrahimDivision of Crop Biotechnics, Department of Biosystems, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0003-0603-7755
Marc Van MontaguDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium; marc.vanmontagu@ugent.be barbara.deconinck@kuleuven.be laurens.pauwels@psb.vib-ugent.be.ORCID 0000-0003-4711-5131
Jeroen WagemansLaboratory of Gene Technology, Department of Biosystems, Division Animal and Human Health Engineering, KU Leuven, 3001 Leuven, Belgium.ORCID 0000-0002-2185-5724
Thomas B JacobsDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0002-5408-492X
Barbara De ConinckDivision of Crop Biotechnics, Department of Biosystems, KU Leuven, 3001 Leuven, Belgium; marc.vanmontagu@ugent.be barbara.deconinck@kuleuven.be laurens.pauwels@psb.vib-ugent.be.ORCID 0000-0002-9349-5086
Laurens PauwelsDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium; marc.vanmontagu@ugent.be barbara.deconinck@kuleuven.be laurens.pauwels@psb.vib-ugent.be.ORCID 0000-0002-0221-9052
Ghent University · BEKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgrobacteriumAgrobacterium tumefaciensClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Associated ProteinsCRISPR-Cas SystemsDNA, PlantGene EditingGenes, PlantGenome, PlantMutagenesisMutationZea maysCRISPR-Associated ProteinsDNA, PlantAgrobacteriumbase editingCRISPRhairy root diseaseplant transformation

Identifiers

PMID33443212
PMCPMC7812762
OpenAlexW3118233706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.