Evidence map›Paper›PMID 33443122›Full record

ArticlemBio2020

Combined and Distinct Roles of Agr Proteins in Clostridioides difficile 630 Sporulation, Motility, and Toxin Production.

Ummey Khalecha Bintha Ahmed, Tyler M Shadid, Jason L Larabee, Jimmy D Ballard

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
0.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 35 citations in OpenAlex.

  1. Polystyrene microplastics facilitateApplied and environmental microbiology · 2026
    Article
  2. Article
  3. Article
  4. Comparative genomic analysis ofMicrobial genomics · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. The sigma factor σFrontiers in microbiology · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Identification of DraRS inJournal of bacteriology · 2023
    Article
  13. Review
  14. Article
  15. Biofilm Formation ofMicroorganisms · 2023
    Review
  16. Article
  17. The RgaS-RgaR two-component system promotesbioRxiv : the preprint server for biology · 2023
    Article
  18. Article
  19. Regulatory transcription factors ofCritical reviews in microbiology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ummey Khalecha Bintha AhmedDepartment of Microbiology and Immunology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Tyler M ShadidDepartment of Microbiology and Immunology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Jason L LarabeeDepartment of Microbiology and Immunology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Jimmy D BallardDepartment of Microbiology and Immunology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA jimmy-ballard@ouhsc.edu.ORCID 0000-0001-8824-9609
University of Oklahoma Health Sciences Center · US

Funding

Differential Effects of TcdB1 and TcdB2 in C. difficile diseaseR01AI119048 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI BALLARD, JIMMY D. · 2015 to 2024
$3.8M
NIAID NIH HHS R01 AI119048
6 · The paper itself

Abstract

The

Indexed as

Gene Expression Regulation, BacterialBacterial ProteinsBacterial ToxinsClostridioides difficileCRISPR-Cas SystemsMovementMutationPhenotypePhylogenySignal TransductionSpores, BacterialBacterial ProteinsBacterial ToxinsAgrautoinducing peptideCas9Clostridioides difficileClostridium difficilesporulationTcdATcdB

Identifiers

PMID33443122
PMCPMC8534292
OpenAlexW3114438533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.