Evidence map›Paper›PMID 33443096›Full record

ArticleJournal of the American Society of Nephrology : JASN2021

Racial Differences in AKI Incidence Following Percutaneous Coronary Intervention.

Joseph Lunyera, Robert M Clare, Karen Chiswell, Julia J Scialla, Patrick H Pun, Kevin L Thomas, Monique A Starks, Clarissa J Diamantidis

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  7. Racial/Ethnic, Sex, and Economic Disparities in the Utilization and Outcomes of Intracoronary Imaging.Journal of the Society for Cardiovascular Angiography & Interventions · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Black and White Adults With CKD Hospitalized With Acute Kidney Injury: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2022
    Article
  15. The Effects of Race on Acute Kidney Injury.Journal of clinical medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joseph LunyeraDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0002-9350-320
Robert M ClareDuke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Karen ChiswellDuke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Julia J SciallaDepartments of Medicine and Public Health Sciences, University of Virginia School of Medicine, Charlottesville, Virginia.
Patrick H PunDuke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Kevin L ThomasDuke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Monique A StarksDuke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Clarissa J DiamantidisDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.ORCID 0000-0001-8212-6288

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUndergoing percutaneous coronary intervention (PCI) is a risk factor for AKI development, but few studies have quantified racial differences in AKI incidence after this procedure.

methodsWe examined the association of self-reported race (Black, White, or other) and baseline eGFR with AKI incidence among patients who underwent PCI at Duke University Medical Center between January 1, 2003, and December 31, 2013. We defined AKI as a 0.3 mg/dl absolute increase in serum creatinine within 48 hours, or ≥1.5-fold relative elevation within 7 days post-PCI from the reference value ascertained within 30 days before PCI.

resultsOf 9422 patients in the analytic cohort (median age 63 years; 33% female; 75% White, 20% Black, 5% other race), 9% developed AKI overall (14% of Black, 8% of White, 10% of others). After adjustment for demographics, socioeconomic status, comorbidities, predisposing medications, PCI indication, periprocedural AKI prophylaxis, and PCI procedural characteristics, Black race was associated with increased odds for incident AKI compared with White race (odds ratio [OR], 1.79; 95% confidence interval [95% CI], 1.48 to 2.15). Compared with Whites, odds for incident AKI were not significantly higher in other patients (OR, 1.30; 95% CI, 0.93 to 1.83). Low baseline eGFR was associated with graded, higher odds of AKI incidence (

conclusionsBlack patients had greater odds of developing AKI after PCI compared with White patients. Future investigations should identify factors, including multiple domains of social determinants, that predispose Black individuals to disparate AKI risk after PCI.

Indexed as

Race FactorsAcute Kidney InjuryAgedBlack or African AmericanCohort StudiesFemaleGlomerular Filtration RateHumansIncidenceMaleMiddle AgedNorth CarolinaOdds RatioPercutaneous Coronary InterventionPreoperative PeriodRisk Factorsacute kidney injuryAfrican Americanspercutaneous coronary interventionracial disparities

Identifiers

PMID33443096
PMCPMC7920184

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.