ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
Age-Related Increases in Posterior Hippocampal Granularity Are Associated with Remote Detailed Episodic Memory in Development.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Neural correlates of learning speed reveal developmental differences in memory.Developmental cognitive neuroscience · 2026Article
- Neural focalization of dorsolateral prefrontal cortex and the inferior parietal lobule is associated with inhibitory control performance in adolescence.Developmental cognitive neuroscience · 2026Article
- The hippocampus becomes topographically and functionally specialized along the longitudinal axis with development.Nature communications · 2026Article
- Increasing representational capacity in the hippocampal-frontoparietal system underlies hierarchical development of temporal memory.Developmental cognitive neuroscience · 2026Review
- Neural Representations of Reward-Related Memories Shift across Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Spontaneous reinstatement of episodic memories in the developing human brain.bioRxiv : the preprint server for biology · 2025Article
- Reinforcement learning increasingly relates to memory specificity from childhood to adulthood.Nature communications · 2025Article
- Differentiation of Related Events in Hippocampus Supports Memory Reinstatement in Development.Journal of cognitive neuroscience · 2025Article
- The mind, brain, and body study: A protocol for examining the effects of the gut-brain-immune axis on internalizing symptoms in youth exposed to caregiving-related early adversity.Brain, behavior, & immunity - health · 2024Article
- The effects of parental presence on amygdala and mPFC activation during fear conditioning: An exploratory study.Developmental science · 2024Article
- Article
- Extended trajectory of spatial memory errors in typical and atypical development: The role of binding and precision.Hippocampus · 2023Article
- Data-Driven Clustering of Functional Signals Reveals Gradients in Processing Both within the Anterior Hippocampus and across Its Long Axis.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Reward Enhances Memory via Age-Varying Online and Offline Neural Mechanisms across Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Higher-dimensional neural representations predict better episodic memory.Science advances · 2022Article
- Developmental differences in memory reactivation relate to encoding and inference in the human brain.Nature human behaviour · 2022Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
Episodic memory is critical to human functioning. In adults, episodic memory involves a distributed neural circuit in which the hippocampus plays a central role. As episodic memory abilities continue to develop across childhood and into adolescence, studying episodic memory maturation can provide insight into the development and construction of these hippocampal networks, and ultimately clues to their function in adulthood. While past developmental studies have shown that the hippocampus helps to support memory in middle childhood and adolescence, the extent to which ongoing maturation within the hippocampus contributes to developmental change in episodic memory abilities remains unclear. In contrast, slower maturing regions, such as the PFC, have been suggested to be the neurobiological locus of memory improvements into adolescence. However, it is also possible that the methods used to detect hippocampal development during middle childhood and adolescence are not sensitive enough. Here, we examine how temporal covariance (or differentiation) in voxel representations within anterior and posterior hippocampus change with age to support the development of detailed recollection in male and female developing humans. We find age-related increases in the distinctiveness of temporal activation profiles in the posterior, but not anterior, hippocampus. Second, we show that this measure of granularity, when present during postencoding rest periods, correlates with the recall of detailed memories of preceding stimuli several weeks postencoding, suggesting that granularity may promote memory stabilization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.