Evidence map›Paper›PMID 33442955›Full record

ReviewThe plant genome2021

Status and prospects of genome-wide association studies in plants.

Laura Tibbs Cortes, Zhiwu Zhang, Jianming Yu

Abstract readReview
In one paragraph

Review in The plant genome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 234 papers.

0numbers the graph read from it
0cells of the map it votes in
234citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

234 citing papers in PubMed.

  1. Article
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  5. Review
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  7. Review
  8. A CThe New phytologist · 2026
    Article
  9. Article
  10. Characterization of oat chromosome rearrangements in advanced breeding lines and implications for genetic improvement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  11. Article
  12. Mining ofHorticulture research · 2026
    Article
  13. Review
  14. Article
  15. Article
  16. Harnessing artificial intelligence in plant breeding: innovations in digital phenotyping and breeding methodologies.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Review
  17. Article
  18. Article
  19. The Paraphyletic Origins of Genetic Resistance to Cabbage Stem Flea Beetle inPlant-environment interactions (Hoboken, N.J.) · 2026
    Article
  20. Article

174 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laura Tibbs CortesDepartment of Agronomy, Iowa State University, Ames, IA, 50010, USA.ORCID 0000-0003-3188-6820
Zhiwu ZhangDepartment of Crop and Soil Sciences, Washington State University, Pullman, WA, 99164, USA.ORCID 0000-0002-5784-9684
Jianming YuDepartment of Agronomy, Iowa State University, Ames, IA, 50010, USA.ORCID 0000-0001-5326-3099

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome-wide association studies (GWAS) have developed into a powerful and ubiquitous tool for the investigation of complex traits. In large part, this was fueled by advances in genomic technology, enabling us to examine genome-wide genetic variants across diverse genetic materials. The development of the mixed model framework for GWAS dramatically reduced the number of false positives compared with naïve methods. Building on this foundation, many methods have since been developed to increase computational speed or improve statistical power in GWAS. These methods have allowed the detection of genomic variants associated with either traditional agronomic phenotypes or biochemical and molecular phenotypes. In turn, these associations enable applications in gene cloning and in accelerated crop breeding through marker assisted selection or genetic engineering. Current topics of investigation include rare-variant analysis, synthetic associations, optimizing the choice of GWAS model, and utilizing GWAS results to advance knowledge of biological processes. Ongoing research in these areas will facilitate further advances in GWAS methods and their applications.

Indexed as

Genome-Wide Association StudyPolymorphism, Single NucleotideGenomicsPhenotype

Identifiers

PMID33442955
PMCPMC12806871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.