Evidence map›Paper›PMID 33442596›Full record

ArticleEuropean heart journal. Case reports2020

Corona Virus Disease 2019

Mireya Castro-Verdes, Antonia Gkouma, John Wort, Carole Ridge, Saeed Mirsadraee, Simon Padley, Awais Sheikh, Suveer Singh

Open access · goldAbstract read
In one paragraph

Article in European heart journal. Case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Aortic floating thrombus in patients with COVID-19: a report of eight cases.General thoracic and cardiovascular surgery · 2025
    Article
  2. Catastrophic Concomitant Arterial and Venous Thrombosis in a Mild COVID-19-Positive Patient.The International journal of angiology : official publication of the International College of Angiology, Inc · 2023
    Article
  3. Stroke Treatment in the Era of COVID-19: a Review.Current treatment options in neurology · 2022
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mireya Castro-VerdesDepartment of Cardiology, Royal Brompton and Harefield NHS Foundation Trust, London, UK.ORCID 0000-0003-1597-7431
Antonia GkoumaDepartment of Cardiothoracic Surgery, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
John WortDepartment of Cardiology, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
Carole RidgeDepartment of Radiology, Royal Brompton and Harefield NHS Foundation Trust, London, UK.ORCID 0000-0003-2510-5856
Saeed MirsadraeeDepartment of Radiology, Royal Brompton and Harefield NHS Foundation Trust, London, UK.ORCID 0000-0003-3051-4355
Simon PadleyDepartment of Radiology, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
Awais SheikhDepartment of Intensive Care, Royal Brompton and Harefield NHS Foundation Trust, London, UK.ORCID 0000-0002-7707-226X
Suveer SinghDepartment of Intensive Care, Royal Brompton and Harefield NHS Foundation Trust, London, UK.ORCID 0000-0003-3219-8966
Royal Brompton & Harefield NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCorona Virus Disease 2019 (COVID-19) pneumonitis associated with severe respiratory failure carries a high mortality. Coagulopathy has emerged as a significant contributor to thrombotic complications. CASE SUMMARY: We describe two cases of severe COVID-19 pneumonitis refractory to conventional mechanical ventilation and proning position, transferred to our specialist centre for cardiorespiratory failure. Cross-sectional imaging demonstrated concurrent venous and aortic thrombosis with end-organ ischaemic changes. One patient received thrombolysis with a partial response. This could not be offered to the other patient due to a recent haemorrhagic event. Both patients died of multi-organ failure in the hospital. DISCUSSION: Concurrent aortic and venous thromboses are rare. This finding in COVID-19 cases, who were both critically ill patients, likely reflects the strongly thrombogenic nature of this illness which ultimately contributed to poor outcomes. The absence of deep vein thrombosis or a potential systemic source of embolism suggests

Indexed as

Arterial thrombosisCase series/case reportsCOVID-19ThrombolysisVenous thrombosis

Identifiers

PMID33442596
PMCPMC7793039
OpenAlexW3112485739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.