ArticleInnovation in aging2021
Higher Fatigue Prospectively Increases the Risk of Falls in Older Men.
Article in Innovation in aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Impact of mixed power training on fall predictors and gait parameters in community-dwelling older men.European journal of applied physiology · 2026Article
- Association of real life postural transitions kinematics with fatigue in neurodegenerative and immune diseases.NPJ digital medicine · 2025Article
- Correlation between postural stability and fall risk in trans-femoral amputees due to muscle fatigue.Journal of physical therapy science · 2024Article
- Functional Near-Infrared Spectroscopy-Based Evidence of the Cerebral Oxygenation and Network Characteristics of Upper Limb Fatigue.Bioengineering (Basel, Switzerland) · 2023Article
- Role of Perceived Physical and Mental Fatigability Severity on Prospective, Recurrent, and Injurious Fall Risk in Older Men.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Therapeutic dilemmas: cognitive enhancers and risk of falling in older adults-a clinical review.European geriatric medicine · 2023Review
- A Multi-Dimensional Model of Fatigue in Old Age: Implications for Brain Aging.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023Article
- Living Alone, Environmental Hazards, and Falls Among U.S. Older Adults.Innovation in aging · 2023Article
- Interaction between age and fatigue on antagonist muscle coactivation during an acute post-fatigue recovery phase.Frontiers in aging · 2022Article
- Fetal muscle extract improves muscle function and performance in aged mice.Frontiers in physiology · 2022Article
- Similar strength gains at lower perceived efforts via cluster set vs. traditional home-based online training: A 6 weeks randomized controlled trial.Frontiers in sports and active living · 2022Article
- Association Between Fatigue and Falls Risk Among the Elderly Aged Over 75 Years in China: The Chain Mediating Role of Falls Efficacy and Lower Limb Function.Frontiers in public health · 2022Article
- Declining energy predicts incident mobility disability and mortality risk in healthy older adults.Journal of the American Geriatrics Society · 2021Article
- Effect of Lower Limb Muscle Fatigue on Fall Risk for Transfemoral Amputee: A Pilot Study.Occupational therapy international · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesFatigue is a common complaint and shares many risk factors with falls, yet the independent contribution of fatigue on fall risk is unclear. This study's primary aim was to assess the association between fatigue and prospective fall risk in 5642 men aged 64-100 enrolled in the Osteoporotic Fractures in Men Study (MrOS). The secondary aim was to examine the association between fatigue and recurrent fall risk. RESEARCH DESIGN AND
methodsFatigue was measured at baseline using the Medical Outcomes Study (short form) single-item question "During the past four weeks, how much of the time did you feel energetic?" Responses were then classified: higher fatigue = "none," "a little," or "some" of the time and lower fatigue = "a good bit," "most," or "all" of the time. We assessed falls using triannual questionnaires. Fall risk was examined prospectively over 3 years; recurrent falling was defined as at least 2 falls within the first year. Generalized estimating equations and multinomial logistic regression modeled prospective and recurrent fall risk as a function of baseline fatigue status, adjusted for demographics, medications, physical activity, and gait speed.
resultsMen with higher (26%) versus lower baseline fatigue were older (75.1 ± 6.2 vs 73.2 ± 5.7 years), 24% less active, and had worse physical function (gait speed = 1.09 ± 0.24 vs 1.24 ± 0.21 m/s), all DISCUSSION AND IMPLICATIONS: Fatigue is an important risk factor of falling independent of established risk factors. Reductions in fatigue (ie, increased energy) may lessen the burden of falls in older men and provide a novel avenue for fall risk intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.