Evidence map›Paper›PMID 33442507›Full record

Article3 Biotech2021

Purification of recombinant human chemokine CCL2 in

Wei Liu, Lei Wang, Jiajia Zhang, Liuhui Qiao, Yiqing Liu, Xinke Yang, Jinghua Zhang, Wenming Zheng, Zhenling Ma

Open access · greenAbstract read
In one paragraph

Article in 3 Biotech, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wei Liu *College of Life Sciences, Henan Agricultural University, Zhengzhou, 450002 China.
Lei Wang *College of Life Sciences, Henan Agricultural University, Zhengzhou, 450002 China.
Jiajia ZhangCollege of Life Sciences, Henan Agricultural University, Zhengzhou, 450002 China.
Liuhui QiaoCollege of Life Sciences, Henan Agricultural University, Zhengzhou, 450002 China.
Yiqing LiuCollege of Life Sciences, Henan Agricultural University, Zhengzhou, 450002 China.
Xinke YangCollege of Life Sciences, Henan Agricultural University, Zhengzhou, 450002 China.
Jinghua ZhangCollege of Life Sciences, Henan Agricultural University, Zhengzhou, 450002 China.
Wenming ZhengCollege of Life Sciences, Henan Agricultural University, Zhengzhou, 450002 China.
Zhenling MaCollege of Life Sciences, Henan Agricultural University, Zhengzhou, 450002 China.ORCID 0000-0002-4791-928X
Henan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemokine (CC-motif) ligand 2 (CCL2) is an inflammatory cytokine that regulates the infiltration and migration of monocytes. It is highly expressed by both tumor and stromal cells and has been associated with tumorigenesis. However, the effect of the exogenous administration of CCL2 on ovarian cancer remains largely unknown. In this report, we attempted to establish an expression system in SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13205-020-02571-0.

Indexed as

Cell proliferationCell signaling pathwayOvarian cancer cellProtein purificationrhCCL2

Identifiers

PMID33442507
PMCPMC7778648
OpenAlexW3118500062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.