Evidence map›Paper›PMID 33442427›Full record

ArticleChemCatChem2020

Regioselectivity of Cobalamin-Dependent Methyltransferase Can Be Tuned by Reaction Conditions and Substrate.

Simona Pompei, Christopher Grimm, Judith E Farnberger, Lukas Schober, Wolfgang Kroutil

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemCatChem, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. New Trends and Future Opportunities in the Enzymatic Formation of C-C, C-N, and C-O bonds.Chembiochem : a European journal of chemical biology · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Simona PompeiInstitute of Chemistry NAWI Graz University of Graz Heinrichstrasse 28 8010 Graz Austria.
Christopher GrimmInstitute of Chemistry NAWI Graz University of Graz Heinrichstrasse 28 8010 Graz Austria.
Judith E FarnbergerAustrian Centre of Industrial Biotechnology c/o Institute of Chemistry University of Graz Heinrichstrasse 28 8010 Graz Austria.
Lukas SchoberInstitute of Chemistry NAWI Graz University of Graz Heinrichstrasse 28 8010 Graz Austria.
Wolfgang KroutilInstitute of Chemistry NAWI Graz University of Graz Heinrichstrasse 28 8010 Graz Austria.ORCID 0000-0002-2151-6394
University of Graz · AT

Funding

Austrian Science Fund FWF P 30920
6 · The paper itself

Abstract

Regioselective reactions represent a significant challenge for organic chemistry. Here the regioselective methylation of a single hydroxy group of 4-substituted catechols was investigated employing the cobalamin-dependent methyltransferase from

Indexed as

biocatalysiscobalamin-dependent methyltransferasesmedium engineeringmethylationregioselectivity

Identifiers

PMID33442427
PMCPMC7783988
OpenAlexW3089557899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.