ArticleRisk management and healthcare policy2021
Preoperative Prognostic Nutritional Index Value is Related to Postoperative Delirium in Elderly Patients After Noncardiac Surgery: A Retrospective Cohort Study.
Article in Risk management and healthcare policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06603129 (Evaluation of the Relationship Between Preoperative Prognostic Nutritional Index and Postoperative Delirium in Gastrointestinal Cancer Surgery), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Relationship Between Preoperative Prognostic Nutritional Index and Postoperative Delirium in Gastrointestinal Cancer Surgery
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Association of preoperative prognostic nutritional index with risk of postoperative delirium: A systematic review and meta-analysis.Frontiers in medicine · 2022Pooled it
- Patterns of Recurrence in Adenocarcinoma of the Esophagogastric Junction: ERECS Trial Post Hoc Analysis.Annals of surgical oncology · 2026Article
- Association between enteral nutrition timing and postoperative anion gap trajectory in cardiac surgery ICU patients: a retrospective study based on the MIMIC-IV database.Journal of cardiothoracic surgery · 2026Article
- Predicting Postoperative Complications in Lung Cancer Spinal Metastases: A Nomogram Based on Nutritional, Low Psoas Muscle Index, and Functional Status.Current oncology (Toronto, Ont.) · 2026Article
- A higher prognostic nutritional index is inversely associated with the need for renal replacement therapy in elderly critically Ill surgical patients.BMC surgery · 2025Article
- Assessment of malnutrition risk and analysis of influencing factors in patients with chronic kidney disease: A cross-sectional survey.BMC nutrition · 2025Article
- Serum IgA, IgG, IgM levels, total protein (TP), albumin (ALB) changes in elderly hip fracture patients after surgery and nutritional support.Journal of medical biochemistry · 2025Article
- Construction of a nomogram prediction model for early postoperative stoma complications of colorectal cancer.World journal of gastrointestinal surgery · 2025Article
- Preoperative Prognostic Nutritional Index Is a Predictive Factor for Postoperative Delirium in Elderly Patients with Femoral Neck Fracture.Clinical interventions in aging · 2025Article
- The predictive value comparison of the different nutritional assessment tools for postoperative delirium in elderly patients after non-cardiac surgery.Frontiers in nutrition · 2025Article
- Comparative predictive value of preoperative GNRI, PNI, and CONUT for postoperative delirium in geriatric abdominal surgery patients admitted to the ICU.Frontiers in nutrition · 2025Article
- Frailty and nutritional assessments for predicting postoperative complications in older adults undergoing non-cardiac surgery.Frontiers in medicine · 2025Article
- CRP/albumin, Glasgow prognostic score, and prognostic nutritional index as a predictor of mortality among delirium patients.Irish journal of medical science · 2024Article
- Preoperative prognostic nutritional index value as a predictive factor for postoperative delirium in older adult patients with hip fractures: a secondary analysis.BMC geriatrics · 2024Observational
- Correlation analysis between plasma biomarkers albumin, fibrinogen, and their ratio with postoperative delirium in patients undergoing non-cardiac surgery: a systematic review and meta-analysis.American journal of translational research · 2024Review
- Clinical Significance of the Prognostic Nutritional Index in Predicting Delirium among Critically Ill Patients: A Retrospective Cohort Study.Critical care research and practice · 2024Article
- Predicative factors and development of a nomogram for postoperative delayed neurocognitive recovery in elderly patients with gastric cancer.Aging clinical and experimental research · 2023Article
- Inflammatory and nutritional markers predict the risk of post-operative delirium in elderly patients following total hip arthroplasty.Frontiers in nutrition · 2023Article
- Observational
- Brain Prehabilitation for Oncologic Surgery.Current oncology reports · 2022Review
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMalnutrition has been considered as a risk factor for postoperative delirium (POD). The Prognostic Nutritional Index (PNI) is a validated tool for assessing nutritional status. This study aimed to investigate the association between preoperative PNI values and the occurrence of POD in elderly surgical patients.
methodsThe retrospective cohort study included 361 elderly individuals who underwent noncardiac surgery between 2018 and 2019. Perioperative data were collected from the patients' medical records. PNI was used to evaluate preoperative nutritional status. The primary outcome was the occurrence of POD. Univariate and multivariate logistic regression analyses were used to identify key factors associated with POD and assess the relationship between PNI values and the occurrence of POD. Receiver operating characteristic (ROC) curve analysis was used to assess the predictive value of PNI for POD.
resultsSeventy-two (19.9%) individuals developed postoperative delirium after surgery. Compared with patients of normal nutrition status (PNI ≥ 50), mild malnutrition (PNI 45-50) did not increase the risk of POD, while patients with moderate to severe malnutrition (PNI 40-45) (odds ratio [OR], 2.92; 95% confidence interval [CI], 1.31-6.50) and serious malnutrition (PNI < 40) (OR, 3.15; 95% CI, 1.12-8.83) were more likely to develop POD. The cut-off value of PNI was 46.05 by ROC curve analysis, the area under the curve (AUC) was 0.69 (95% CI 0.62-0.77).
conclusionPreoperative PNI value is related to postoperative delirium in elderly patients after noncardiac surgery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.