Evidence map›Paper›PMID 33442256›Full record

ArticleTherapeutics and clinical risk management2021

Clinical Features for Severely and Critically Ill Patients with COVID-19 in Shandong: A Retrospective Cohort Study.

Shengyu Zhou, Jiawei Xu, Wenqing Sun, Jintao Zhang, Fayan Zhang, Xuesong Zhao, Ximing Wang, Wei Zhang, Yu Li, Kang Ning and 20 more

Open access · goldAbstract read
In one paragraph

Article in Therapeutics and clinical risk management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Lymphadenopathy afterBiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 18 institutions in 1 country.

Shengyu Zhou *Department of Respiratory and Critical Care Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Jiawei Xu *Department of Respiratory and Critical Care Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.ORCID 0000-0002-6289-5589
Wenqing SunIntensive Care Unit, Shandong Provincial Chest Hospital, Jinan, People's Republic of China.
Jintao ZhangDepartment of Respiratory and Critical Care Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Fayan ZhangCollege of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, People's Republic of China.
Xuesong ZhaoDepartment of Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People's Republic of China.
Ximing WangDepartment of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong University, Jinan, People's Republic of China.
Wei ZhangDepartment of Lung Disease, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, People's Republic of China.ORCID 0000-0001-9004-1161
Yu LiDepartment of Respiratory and Critical Care Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Kang NingThe First Affiliated Hospital of Shandong First Medical University Shandong Provincial Qianfoshan Hospital, Jinan, People's Republic of China.
Yun PanDepartment of Respiratory and Critical Care Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Tian LiuDepartment of Respiratory and Critical Care Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Jiping ZhaoDepartment of Respiratory and Critical Care Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Jiguang YuDepartment of Infectious Diseases, Qishan Hospital, Yantai, People's Republic of China.
Yunbo SunAffiliated Hospital of Qingdao University, Qingdao, People's Republic of China.
Feng GaoDepartment of Infectious Disease, Linyi People's Hospital, Linyi, People's Republic of China.
Rumin ZhangDepartment of Critical Care Medicine, Zibo Central Hospital, Zibo, People's Republic of China.
Chunsheng FuLiaocheng Contagion Hospital, Liaocheng, People's Republic of China.
Yu SunJining Hospital of Infectious Diseases, Jining, People's Republic of China.
Xiuhe OuyangDepartment of Respiratory and Critical Medicine, Binzhou People's Hospital, Binzhou, People's Republic of China.
Fusen ZhangIntensive Care Unit, Taian City Central Hospital, Taian, People's Republic of China.
Qing HuDepartment of Respiratory Medicine, Heze Municipal Hospital, Heze, People's Republic of China.
Haifeng TengWeihai Municipal Hospital, Weihai, People's Republic of China.
Yun LiJinan Central Hospital, Jinan, People's Republic of China.
Chunke ZhangWeihai Central Hospital, Weihai, People's Republic of China.
Wei TanDepartment of Respiratory Medicine, Weifang People's Hospital, Weifang, People's Republic of China.
Jinlai LiIntensive Care Unit, Zaozhuang Municipal Hospital, Zaozhuang, People's Republic of China.
Lixia YinDepartment of Respiratory Medicine, Dezhou People's Hospital, Dezhou, People's Republic of China.
Liang DongDepartment of Respiratory and Critical Care Medicine, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Chunting WangDepartment of Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People's Republic of China.
Qilu Hospital of Shandong University · CNJinan Central Hospital · CNQingdao University · CNShandong Provincial Hospital · CNShandong University · CNShandong University of Traditional Chinese Medicine · CNAffiliated Hospital of Shandong University of Traditional Chinese Medicine · CNBinzhou People's Hospital · CNCentral Hospital of Zibo · CNDezhou University · CNHeze Municipal Hospital · CNLiaocheng People's Hospital · CNLinyi People's Hospital · CNShandong Chest Hospital · CNShandong Provincial QianFoShan Hospital · CNWeifang People's Hospital · CNWeihai Municipal Hospital · CNZaozhuang Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel pathogen, has caused an outbreak of coronavirus disease 2019 (COVID-19) that has spread rapidly around the world. Determining the risk factors for death and the differences in clinical features between severely ill and critically ill patients with SARS-CoV-2 pneumonia has become increasingly important.

aimThis study was intended to provide insight into the difference between severely ill and critically ill patients with SARS-CoV-2 pneumonia.

methodsIn this retrospective, multicenter cohort study, we enrolled 62 seriously ill patients with SARS-CoV-2 pneumonia who had been diagnosed by March 12, 2020. Clinical data, laboratory indexes, chest images, and treatment strategies collected from routine medical records were compared between severely ill and critically ill patients. Univariate and multivariate logistic regression analyses were also conducted to identify the risk factors associated with the progression of patients with severe COVID-19.

resultsOf the 62 patients with severe or critical illness, including 7 who died, 30 (48%) patients had underlying diseases, of which the most common was cardiovascular disease (hypertension, 34%, and coronary heart disease, 5%). Compared to patients with severe disease, those with critical disease had distinctly higher white blood cell counts, procalcitonin levels, and D-dimer levels, and lower hemoglobin levels and lymphocyte counts. Multivariate regression showed that a lymphocyte count less than 10

conclusionBased on multivariate regression analysis, a lower lymphocyte count (<10

Indexed as

clinical featuresCOVID-19critically ill patientsSARS-CoV-2severely ill patients

Identifiers

PMID33442256
PMCPMC7797329
OpenAlexW3118743602

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.