ArticleJournal of the ASEAN Federation of Endocrine Societies2019
Methimazole-Induced Aplastic Anemia with Concomitant Hepatitis in a Young Filipina with Graves' Disease.
Article in Journal of the ASEAN Federation of Endocrine Societies, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Methimazole-Induced Pancytopenia in a Patient with Graves' Disease: A Case Report and Literature Review.Current drug safety · 2025Review
- Aplastic anemia in a patient with papillary thyroid carcinoma complicated with Hashimoto's thyroiditis: a case report.Frontiers in oncology · 2024Article
- Concomitant methimazole-induced agranulocytosis and cholestatic jaundice in a young woman.BMJ case reports · 2022Article
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2 authors.
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Abstract
A 34-year-old female Filipino with Graves' disease on methimazole came in due to fever, sore throat and jaundice. She was initially diagnosed with methimazole-induced agranulocytosis and drug-induced liver injury. She was treated with intravenous broad-spectrum antibiotic and granulocyte colony stimulating factor. On day 4 of admission, she developed pancytopenia and was managed as methimazole-induced aplastic anemia. She was started on steroid therapy and received 1 unit of packed red blood cell. The jaundice also increased, hence, she was given ursodeoxycholic acid. On day 9 of admission, with the consideration of "lineage steal phenomenon," biopsy was done and eltrombopag was started. Patient was discharged stable at 12th hospital day. This case presents 3 rare life-threatening complications of methimazole namely: agranulocytosis, aplastic anemia and hepatitis.
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