ArticleJournal of the ASEAN Federation of Endocrine Societies2017
Risk Factors Associated with the Activity and Severity of Graves' Ophthalmopathy among Patients at the University of the Philippines Manila-Philippine General Hospital.
Article in Journal of the ASEAN Federation of Endocrine Societies, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 12 citations in OpenAlex.
- Prediction of exophthalmos by body mass index for craniofacial reconstruction: consequences for cold cases.Forensic science, medicine, and pathology · 2024Article
- Assessment of the levels of interleukin-17 and interleukin-38 in thyroid-associated ophthalmopathy patients.International ophthalmology · 2023Article
- Factors associated with severity of orbitopathy in patients with Graves' disease.Taiwan journal of ophthalmologyArticle
- Epidemiological Status of Thyroid Eye Disease in Central Iran.Journal of current ophthalmologyArticle
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Authors and funding
9 authors at 2 institutions in 1 country.
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Abstract
backgroundAsians with Graves' ophthalmopathy (GO) may have earlier compressive features due to narrower orbital apex and increased orbital volume.
objectiveTo determine the risk factors associated with activity and severity of GO among adults. METHODOLOGY: This was a cross-sectional analytical study of 163 adults with Graves' disease (GD) from the outpatient clinics of the Philippine General Hospital. Demographics, clinical data, thyrotropin receptor antibody (TRAb) and urine iodine (UIE) levels were obtained. All participants were evaluated for activity and severity of GO by a single ophthalmologist.
resultsThe population was predominantly composed of females (81%) and nonsmokers (69%), with a mean age of 35 + 11 years and median GD duration of 2 years. Median TRAb was 8.9 U/L while UIE was 171 mcg/L. Eight percent exhibited active GO, with 85% having mild disease. Multivariate analysis showed male sex to be associated with severe disease (OR 3.71,
conclusionLower rates of active and severe GO were seen compared to previous reports. In this population of predominantly nonsmokers, elevated TRAb emerged as a risk factor for active and severe GO.
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