Evidence map›Paper›PMID 33442002›Full record

ArticleNature medicine2021

Liver metastases inhibit immunotherapy efficacy.

Katherine E Lindblad, Amaia Lujambio

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Katherine E LindbladDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Amaia LujambioDepartment of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. amaia.lujambio@mssm.edu.ORCID http://orcid.org/0000-0002-2798-1481

Funding

TRAINING PROGRAM IN CANCER THERAPYT32CA078207 · NCI · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI James J Manfredi · 1999 to 2026
$11.6M
Translational Immunology Training ProgramT32AI078892 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Karen Leigh Edelblum, SERGIO A. LIRA · 2008 to 2026
$4.5M
Targeting tumor metabolism and immune environment via beta-catenin: Towards precision medicine in HCCR01CA251155 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LUJAMBIO, AMAIA, MONGA, SATDARSHAN SINGH · 2020 to 2024
$3.1M
Tumor-intrinsic signaling pathways restrict anti-tumor immunity in hepatocellular carcinomaR37CA230636 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LUJAMBIO, AMAIA · 2018 to 2024
$2.7M
Damon Runyon Cancer Research Foundation (Cancer Research Fund of the Damon Runyon-Walter Winchell Foundation) DR52-18NCI NIH HHS T32 CA078207U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) 1R01CA251155U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) R37CA230636U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 2T32AI078892
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Liver NeoplasmsT-LymphocytesHumansImmunologic FactorsImmunotherapyMacrophagesImmunologic Factors

Identifiers

PMID33442002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.