Evidence map›Paper›PMID 33441934›Full record

ArticleScientific reports2021

Incidence of cardiovascular events and mortality in Korean patients with chronic kidney disease.

Hyunjin Ryu, Jayoun Kim, Eunjeong Kang, Yeji Hong, Dong-Wan Chae, Kyu Hun Choi, Seung Hyeok Han, Tae Hyun Yoo, Kyubeck Lee, Yong-Soo Kim and 10 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 14 institutions in 1 country.

Hyunjin RyuDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Jayoun KimMedical Research Collaborating Center, Seoul National University Hospital, Seoul, Republic of Korea.
Eunjeong KangDepartment of Internal Medicine, Ewha Womans University Medical Center, Seoul, Republic of Korea.
Yeji HongRehabilitation Medical Research Center, Korea Workers' Compensation and Welfare Service Incheon Hospital, Incheon, Republic of Korea.
Dong-Wan ChaeDepartment of Internal Medicine, Seoul National University Bundang Hospital, Gyeonggi-do, Republic of Korea.
Kyu Hun ChoiDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Seung Hyeok HanDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Tae Hyun YooDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kyubeck LeeDepartment of Internal Medicine, Kangbuk Samsung Hospital, College of Medicine, Sungkyunkwan University, Seoul, Korea.
Yong-Soo KimDepartment of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Republic of Korea.
Wookyung ChungDepartment of Internal Medicine, Gachon University of Medicine and Science, Incheon, Republic of Korea.
Yun Kyu OhDepartment of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
Soo Wan KimDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
Yeong Hoon KimDepartment of Internal Medicine, Inje University College of Medicine, Busan, Korea.
Su Ah SungDepartment of Internal Medicine, Eulji Medical Center, Eulji University, Seoul, Korea.
Joongyub LeeDepartment of Prevention and Management, Inha University Hospital, Incheon, Korea.
Sue K ParkDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Curie AhnDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Kook-Hwan OhDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea. ohchris@hanmail.net.
Representing KNOW-CKD Study Group
Seoul National University Hospital · KRYonsei University · KRSeoul National University · KRCatholic University of Korea · KRChonnam National University · KREulji University · KREwha Womans University Medical Center · KRGachon University · KRIncheon Medical Center · KRInha University Hospital · KRInje University · KRSeoul National University Bundang Hospital · KRSNUH SMG-SNU Boramae Medical Center · KRSungkyunkwan University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few studies have investigated the incidence of cardiovascular disease (CVD) in the Asian chronic kidney disease (CKD) population. This study assessed the incidence of CVD, death, and a composite outcome of CVD and death in a prospective Korean predialysis CKD cohort. From a total of 2179 patients, incidence rates were analyzed, and competing risk analyses were conducted according to CKD stage. Additionally, incidence was compared to the general population. During a median 4.1 years of follow-up, the incidence of CVD, all-cause death, and the composite outcome was 17.2, 9.6, and 24.5 per 1000 person-years, respectively. These values were higher in diabetic vs. non-diabetic subjects (P < 0.001). For all outcomes, incidence rates increased with increasing CKD stage (CVD, P = 0.001; death, P < 0.001; and composite, P < 0.001). Additionally, CKD stage G4 [hazard ratio (HR) 2.8, P = 0.008] and G5 (HR 5.0, P < 0.001) were significant risk factors for the composite outcome compared to stage G1 after adjustment. Compared to the general population, the total cohort population (stages G1-G5) showed significantly higher risk of CVD (HR 2.4, P < 0.001) and the composite outcome (HR 1.7, P < 0.001). The results clearly demonstrate that CKD is a risk factor for CVD in an Asian population.

Indexed as

AdultAgedCardiovascular DiseasesCause of DeathComorbidityDiabetes ComplicationsFemaleHumansIncidenceLongitudinal StudiesMaleMiddle AgedProportional Hazards ModelsProspective StudiesRenal Insufficiency, ChronicRepublic of Korea

Identifiers

PMID33441934
PMCPMC7806882
OpenAlexW3118706861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.