ArticleScientific reports2021
Drug related problems in clinical practice: a cross-sectional study on their prevalence, risk factors and associated pharmaceutical interventions.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 2 of them syntheses that pooled it.
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Who cites it
69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- Intervention of pharmacist included in multidisciplinary team to reduce adverse drug event: a qualitative systematic review.BMC health services research · 2023Pooled it
- Clinical pharmacy services for tuberculosis management: a systematic review.Frontiers in pharmacology · 2023Pooled it
- Pharmacists and community health workers improve medication-related process outcomes among Cambodian Americans with depression and risk for diabetes.Journal of the American Pharmacists Association : JAPhATrial
- Integration and Outcomes of Entrustable Professional Activities Performed by PharmD Trainees at Hospital Practice Sites.Pharmacy (Basel, Switzerland) · 2026Article
- Association between unresolved drug-related problems and 6-month hospital readmissions following pharmacist-led medication reviews: a retrospective observational study.International journal of clinical pharmacy · 2026Observational
- Polypharmacy and unit dose dispensing system (UDDS) in geriatric care : Challenges from the perspective of healthcare staff.Zeitschrift fur Gerontologie und Geriatrie · 2026Article
- A prospective observational study evaluating drug-related problems and their impact on patient-related outcomes in hospitalized epileptic patients.Scientific reports · 2026Observational
- The economic impact of clinical pharmacists in a tertiary care centre in Germany: pharmacoeconomic benefit calculation using cost-avoidance analysis.BMC health services research · 2026Article
- Resolution rate of prescribing errors after advice from a specialised hospital pharmacist or a substitute hospital pharmacist: a retrospective cross-sectional study.European journal of hospital pharmacy : science and practice · 2026Article
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- Prevalence and associated factors for drug-related problems and polypharmacy identified by a pharmacist-led medication review in patients enrolled in a home healthcare program.BMC geriatrics · 2026Observational
- Prospective evaluation of medication-related problems and pharmacist interventions in liver transplant recipients.Frontiers in pharmacology · 2026Article
- Clinical pharmacists and drug-related problem management in a South African hospital.Health SA = SA Gesondheid · 2026Article
- The Spectrum of Clinical Pharmacy Services in a Non-University Hospital-A Comprehensive Characterization Including a Risk Assessment for Drug-Related Problems and Adverse Drug Reactions.Pharmacy (Basel, Switzerland) · 2025Article
- Drug-related problems and challenges encountered by pharmacists in nirmatrelvir/ritonavir counselling during the covid-19 pandemic: a multi-center study.Scientific reports · 2025Article
- Drug related problems and associated factors among thyroid disorder patients in Northwest Ethiopia.Scientific reports · 2025Article
- Optimizing the Pharmacotherapy of Vascular Surgery Patients at Hospital Admission and Discharge (PHAROS): Protocol for a Quasi-Experimental Clinical Uncontrolled Trial.JMIR research protocols · 2025Article
- Analysis of clinical pharmacists' interventions in a rehabilitation setting.Journal of pharmaceutical policy and practice · 2025Article
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9 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Drug-related problems (DRP) cause preventable negative health outcomes, especially during hospital admissions. The aim of our study was to examine the prevalence and characteristics of DRP in regular clinical pharmacy, as well as to determine those factors associated with a higher risk of DRP in the hospital setting. We analyzed data from a standardized registry database of regular pharmacy practice (2015- 2016). DRP were classified according to the Pharmaceutical Care Network Europe v6.2 classification. Cross-sectional data were obtained from 1602 adults admitted to medical wards. Crude and adjusted binary logistic regressions were performed to identify associations between potential risk factors and DRP. Overall DRP prevalence was high across medical specialties (45,1%), in a population characterized by advanced age, polypharmacy and multimorbidity. Problems leading to DRP were mainly classified into two domains (effectiveness and adverse reactions), being drug and dose selection the most frequent causes. Interventions were accepted and DRP were totally or partially solved in 74.1% and 4.81% of cases, respectively. In the adjusted model polypharmacy, allergies, BMI > 25 kg/m2 and clearance < 30 mL/min were associated with a higher risk of DRP. The participation of clinical pharmacists into multidisciplinary teams promotes the detection and solution of DRP. Polypharmacy, obesity, renal impairment and allergy are associated with a higher risk of DRP during admission.
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