Evidence map›Paper›PMID 33441815›Full record

ArticleScientific reports2021

A pilot study for intraocular pressure measurements based on vibroacoustic parameters.

Deukha Kim, Youngbeen Chung, Yeji Yeon, Hyunsoo Cho, Han Woong Lim, Junhong Park, Won June Lee

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Deukha KimDepartment of Mechanical Engineering, Hanyang University College of Engineering, Seoul, Korea.
Youngbeen ChungDepartment of Mechanical Engineering, Hanyang University College of Engineering, Seoul, Korea.
Yeji YeonDepartment of Ophthalmology, Hanyang University College of Medicine, Wangsimni-ro 222, Seongdong-gu, Seoul, 04763, Korea.
Hyunsoo ChoDepartment of Ophthalmology, Hanyang University College of Medicine, Wangsimni-ro 222, Seongdong-gu, Seoul, 04763, Korea.
Han Woong LimDepartment of Ophthalmology, Hanyang University College of Medicine, Wangsimni-ro 222, Seongdong-gu, Seoul, 04763, Korea.
Junhong ParkDepartment of Mechanical Engineering, Hanyang University College of Engineering, Seoul, Korea.
Won June LeeDepartment of Ophthalmology, Hanyang University College of Medicine, Wangsimni-ro 222, Seongdong-gu, Seoul, 04763, Korea. wonjunelee@hanyang.ac.kr.
Hanyang University · KRAnyang University · KRHanyang University Seoul Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to identify vibroacoustic properties associated with intraocular pressure (IOP) changes and to suggest a new way to measure the IOP based on these properties. Ten ex vivo porcine eyeballs were used in this study. Each eyeball was fixated in a central hole of a Styrofoam block, and vibration applied to the Styrofoam block was transmitted to the eyeball. An accelerometer directly attached to the eyeball measured the vibration response. Excitations and measurements were performed for 1 s, and the excitation magnitude was varied for the same signal in repeat measurements. A 30-gauge needle was inserted into the anterior chamber of the eyeball to inject a balanced salt solution, and the height of the bottle was adjusted to adjust the IOP. A tonometer was used under identical conditions to measure the IOP five times, and the mean value was determined for further analyses. The measurements showed that the parameters resonance frequency and change in the magnitude of the vibration response (CMVR) increased with rising IOP values. The CMVR was highly correlated with the IOP (p-value < 0.0001). A linear mixed effects model (LMM) was used as a statistical analysis method. We confirmed that vibroacoustic properties of the eyeball are correlated with IOP changes. It is expected that the CMVR will serve as a new parameter for IOP measurements. Thus, in the future, continuous IOP measurements would be easily performed using the CMVR.

Indexed as

Intraocular PressureTonometry, OcularAcousticsAnimalsEyePilot ProjectsSwineVibration

Identifiers

PMID33441815
PMCPMC7806898
OpenAlexW3119288894

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.