ArticleScientific reports2021
Geographical influences on thyroid abnormalities in adult population from iodine-replete regions: a cross-sectional study.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Prevalence of thyroid disorders in inland and coastal populations: A systematic review.Frontiers in endocrinology · 2026Pooled it
- Iodine intake assessment in the staff of a Porto region university (Portugal): the iMC Salt trial.European journal of nutrition · 2023Trial
- Retrospective analysis of thyroid functions and sonographic characteristics of the thyroid gland in a health check-up population in China during 2020-2024.Frontiers in public health · 2026Article
- Coexistent Hashimoto's thyroiditis modulates lymph node metastasis burden in papillary thyroid carcinoma: a single-center study in South China.Frontiers in endocrinology · 2026Article
- Ocean Acidification, Iodine Bioavailability, and Cardiovascular Health: A Review of Possible Emerging Risks.Journal of cardiovascular development and disease · 2025Review
- Urinary iodine levels and thyroid disorder prevalence in the adult population of China: a large-scale population-based cross-sectional study.Scientific reports · 2025Article
- Prognostic Indicators and Comparative Treatment Outcomes in High-Risk Thyroid Cancer with Laryngotracheal Invasion.Endocrinology and metabolism (Seoul, Korea) · 2025Article
- Normal reference values for Tc-99m pertechnetate thyroid uptake in northern Iranian population: A single-center experience.Caspian journal of internal medicine · 2024Article
- Article
- Thyroid function and epilepsy: a two-sample Mendelian randomization study.Frontiers in human neuroscience · 2023Article
- Hypothyroidism Prevalence in the United States: A Retrospective Study Combining National Health and Nutrition Examination Survey and Claims Data, 2009-2019.Journal of the Endocrine Society · 2022Article
- Thyroid Profile and Factors Associated with Hypothyroidism Among Multidrug-Resistant Tuberculosis Patients Attending Saint Peter's Specialized Hospital Addis Ababa, Ethiopia.Infection and drug resistance · 2021Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The studies on the increasing incidence of thyroid abnormalities are scarce. The aim of this current study was to ascertain the effects of geographical region on thyroid abnormalities under the context of universal salt iodization (USI). We randomly selected 1255 participants residing in inland and 1248 in coast, with the determination of urinary iodine concentration (UIC) and functional and morphological abnormalities of thyroid gland. The median UIC was significantly higher for the inland participants (188.5 μg/L) than the coastal participants (128.5 μg/L; p < 0.001), indicating iodine sufficiency in both populations according to the recommended assessment criteria by the World Health Organization. However, the spectrum of thyroid abnormalities varied between regions, with hypothyroidism prevalent in inland and thyroid nodules in coast. The associations between region and thyroid abnormalities via binary logistic regression models showed that the coastal participants were at a higher risk of total thyroid abnormalities than those from the inland (OR 1.216, 95% CI 1.020-1.449), after the adjustment of ten confounders (demographical characteristics, smoking status, metabolism syndrome, and hyperuricemia). These results indicated that further investigations of the adverse effects of hypothyroidism and thyroid nodules on health burden is urgently needed to sustain USI program.
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