Evidence map›Paper›PMID 33441739›Full record

ArticleScientific reports2021

Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules.

Kasane Imura-Kishi, Aya Uchida, Naoki Tsunekawa, Hitomi Suzuki, Hinako M Takase, Yoshikazu Hirate, Masami Kanai-Azuma, Ryuji Hiramatsu, Masamichi Kurohmaru, Yoshiakira Kanai

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Flow-driven lumen remodeling and valve opening in the vas deferens.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Review
  4. The Biology and Regulation of Spermatogonial Stem Cells in the Niche.Advances in experimental medicine and biology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Mitofusins: from mitochondria to fertility.Cellular and molecular life sciences : CMLS · 2022
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kasane Imura-Kishi *Department of Veterinary Anatomy, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Aya Uchida *Department of Veterinary Anatomy, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Naoki TsunekawaDepartment of Veterinary Anatomy, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Hitomi SuzukiDepartment of Experimental Animal Model for Human Disease, Center for Experimental Animals, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
Hinako M TakaseDepartment of Experimental Animal Model for Human Disease, Center for Experimental Animals, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
Yoshikazu HirateDepartment of Experimental Animal Model for Human Disease, Center for Experimental Animals, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
Masami Kanai-AzumaDepartment of Experimental Animal Model for Human Disease, Center for Experimental Animals, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.
Ryuji HiramatsuDepartment of Veterinary Anatomy, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Masamichi KurohmaruDepartment of Veterinary Anatomy, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Yoshiakira KanaiDepartment of Veterinary Anatomy, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. aykanai@mail.ecc.u-tokyo.ac.jp.
The University of Tokyo · JPTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In mammalian testes, undifferentiated spermatogonia (A

Indexed as

AnimalsCell DifferentiationEpitheliumFibroblast Growth FactorsMaleMiceMice, Inbred C57BLPhosphorylationProto-Oncogene Proteins c-aktProto-Oncogene Proteins c-kitRegenerationRetinoic Acid 4-HydroxylaseSeminiferous TubulesSertoli CellsSignal TransductionSpermatogenesisCyp26a1 protein, mouseFibroblast Growth FactorsKit protein, mouseProto-Oncogene Proteins c-aktProto-Oncogene Proteins c-kitRetinoic Acid 4-HydroxylaseTretinoin

Identifiers

PMID33441739
PMCPMC7806815
OpenAlexW3118731845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.