Evidence map›Paper›PMID 33441620›Full record

ArticleScientific reports2021

Aggregation affects optical properties and photothermal heating of gold nanospheres.

Yiru Wang, Zhe Gao, Zonghu Han, Yilin Liu, Huan Yang, Taner Akkin, Christopher J Hogan, John C Bischof

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Dual-Laser Optical Tweezers for Photothermal Analysis of Hybrid Microgels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Advanced Rewarming Technologies for Cryopreservation.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Plasmonic and Photothermal Properties of Silica-Capped Gold Nanoparticle Aggregates.The journal of physical chemistry. C, Nanomaterials and interfaces · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yiru Wang *Department of Mechanical Engineering, University of Minnesota, Twin Cities, Minneapolis, MN, 55455, USA.
Zhe Gao *Department of Mechanical Engineering, University of Minnesota, Twin Cities, Minneapolis, MN, 55455, USA.
Zonghu HanDepartment of Mechanical Engineering, University of Minnesota, Twin Cities, Minneapolis, MN, 55455, USA.
Yilin LiuDepartment of Mechanical Engineering, University of Minnesota, Twin Cities, Minneapolis, MN, 55455, USA.
Huan YangDepartment of Mechanical Engineering, University of Minnesota, Twin Cities, Minneapolis, MN, 55455, USA.
Taner AkkinDepartment of Biomedical Engineering, University of Minnesota, Twin Cities, Minneapolis, MN, 55455, USA.
Christopher J HoganDepartment of Mechanical Engineering, University of Minnesota, Twin Cities, Minneapolis, MN, 55455, USA.
John C BischofDepartment of Mechanical Engineering, University of Minnesota, Twin Cities, Minneapolis, MN, 55455, USA. bischof@umn.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laser heating of gold nanospheres (GNS) is increasingly prevalent in biomedical applications due to tunable optical properties that determine heating efficiency. Although many geometric parameters (i.e. size, morphology) can affect optical properties of individual GNS and their heating, no specific studies of how GNS aggregation affects heating have been carried out. We posit here that aggregation, which can occur within some biological systems, will significantly impact the optical and therefore heating properties of GNS. To address this, we employed discrete dipole approximation (DDA) simulations, Ultraviolet-Visible spectroscopy (UV-Vis) and laser calorimetry on GNS primary particles with diameters (5, 16, 30 nm) and their aggregates that contain 2 to 30 GNS particles. DDA shows that aggregation can reduce the extinction cross-section on a per particle basis by 17-28%. Experimental measurement by UV-Vis and laser calorimetry on aggregates also show up to a 25% reduction in extinction coefficient and significantly lower heating (~ 10%) compared to dispersed GNS. In addition, comparison of select aggregates shows even larger extinction cross section drops in sparse vs. dense aggregates. This work shows that GNS aggregation can change optical properties and reduce heating and provides a new framework for exploring this effect during laser heating of nanomaterial solutions.

Identifiers

PMID33441620
PMCPMC7806971

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.