ArticleScientific reports2021
Comparison of oral microbiome profiles in 18-month-old infants and their parents.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Exploring Oral Microbiome in Healthy Infants and Children: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Life stage shifts in salivary microbiota determinants: a cross-sectional study in twins.NPJ biofilms and microbiomes · 2026Article
- Mother-to-offspring microbial vertical transmission: timing, determinants, and impact on offspring susceptibility to gastrointestinal diseases.Medical review (2021) · 2026Review
- Unique ecology of co-occurring functionally and phylogenetically undescribed species in the infant oral microbiome.PLoS computational biology · 2026Article
- Integrative insights into the oral microbiome's role in systemic diseases: novel therapeutic strategies and future directions.Antonie van Leeuwenhoek · 2025Review
- The Infant Oral Microbiome: Developmental Dynamics, Modulating Factors, and Implications for Oral and Systemic Health.International journal of molecular sciences · 2025Review
- Dysbiosis of Oral Microbiome: A Key Player in Oral Carcinogenesis? A Critical Review.Biomedicines · 2025Review
- Perinatal factors influencing the earliest establishment of the infant microbiome.Microbiome research reports · 2025Article
- Oral Microbiota Development in the First 60 Months: A Longitudinal Study.Journal of dental research · 2024Article
- Upper respiratory microbial communities of healthy populations are shaped by niche and age.Microbiome · 2024Article
- Helicobacter pylori infection in infant rhesus macaque monkeys is associated with an altered lung and oral microbiome.Scientific reports · 2024Article
- Upper respiratory microbial communities of healthy populations are shaped by niche and age.bioRxiv : the preprint server for biology · 2024Article
- Antimicrobial Properties of Colostrum and Milk.Antibiotics (Basel, Switzerland) · 2024Review
- The contribution of maternal factors to the oral microbiota of the child: Influence from early life and clinical relevance.The Japanese dental science review · 2023Review
- Prediction of Future Caries in 1-Year-Old Children via the Salivary Microbiome.Journal of dental research · 2023Article
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- Upper Respiratory Microbiome in Pregnant Women: Characterization and Influence of Parity.Microorganisms · 2022Article
- Salivary microbiome in children with Down syndrome: a case-control study.BMC oral health · 2022Article
- Study of oral microbiota diversity among groups of families originally from different countries.Saudi journal of biological sciences · 2022Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The onset and progress of dental caries and periodontal disease is associated with the oral microbiome. Therefore, it is important to understand the factors that influence oral microbiome formation. One of the factors that influence oral microbiome formation is the transmission of oral bacteria from parents. However, it remains unclear when the transmission begins, and the difference in contributions of father and mother. Here, we focused on the oral microbiome of 18-month-old infants, at which age deciduous dentition is formed and the oral microbiome is likely to become stable, with that of their parents. We collected saliva from forty 18-month-old infants and their parents and compared the diversity and composition of the microbiome using next-generation sequencing of 16S rRNA genes. The results showed that microbial diversity in infants was significantly lower than that in parents and composition of microbiome were significantly different between infants and parents. Meanwhile, the microbiome of the infants was more similar to that of their mothers than unrelated adults. The bacteria highly shared between infants and parents included not only commensal bacteria but also disease related bacteria. These results suggested that the oral microbiome of the parents influences that of their children aged < 18 months.
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