ArticleTranslational psychiatry2021
Prenatal androgen exposure causes a sexually dimorphic transgenerational increase in offspring susceptibility to anxiety disorders.
Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Neuropsychiatric disorders in children of mothers with polycystic ovary syndrome: a systematic review and meta-analysis.BMC psychiatry · 2026Pooled it
- Efficacy of Acupuncture in Alleviating Negative Emotions in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.Brain and behavior · 2025Pooled it
- Therapeutic effect and safety of curcumin in women with PCOS: A systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Hypoadiponectinemia does not enhance anxiety-like behaviour in a lean PCOS-like mouse model.Scientific reports · 2026Article
- Polyendocrine metabolic ovarian syndrome in pregnancy: pathophysiology and outcomes.Nature reviews. Endocrinology · 2026Review
- A single-nucleus multiomic study of preoptic area cells in prepubertal control vs prenatally androgenized female mice.Endocrinology · 2026Article
- Maternal polycystic ovarian syndrome and offspring psychopathology and neurodevelopment.Human reproduction (Oxford, England) · 2025Review
- Maternal Hyperandrogenemia and the Long-Term Neuropsychological, Sex Developmental, and Metabolic Effects on Offspring.International journal of molecular sciences · 2025Review
- Article
- Exploring the Combination of Traditional Chinese and Allopathic Medicine in the Treatment of Polycystic Ovary Syndrome from the Perspective of Modern Medicine.Drug design, development and therapy · 2025Review
- Psychological symptoms in perimenarcheal adolescents: association with PCOS risk factors.Frontiers in endocrinology · 2025Article
- Obesity is associated with lower levels of negative emotions in polycystic ovary syndrome in clinical and animal studies.Annals of medicine · 2024Article
- Dissecting the Impact of Maternal Androgen Exposure on Developmental Programming through Targeting the Androgen Receptor.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Grandfathers-to-Grandsons Transgenerational Transmission of Exercise Positive Effects on Cognitive Performance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Polycystic ovary syndrome.Nature reviews. Disease primers · 2024Review
- Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse model.Scientific reports · 2024Article
- Paternal impact on the developmental programming of sexual dimorphism.Frontiers in cell and developmental biology · 2024Review
- Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome.Cell reports. Medicine · 2023Article
- Transcriptomic survey of key reproductive and metabolic tissues in mouse models of polycystic ovary syndrome.Communications biology · 2023Article
- Prenatal Androgen Excess Induces Multigenerational Effects on Female and Male Descendants.Clinical medicine insights. Endocrinology and diabetes · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
If and how obesity and elevated androgens in women with polycystic ovary syndrome (PCOS) affect their offspring's psychiatric health is unclear. Using data from Swedish population health registers, we showed that daughters of mothers with PCOS have a 78% increased risk of being diagnosed with anxiety disorders. We next generated a PCOS-like mouse (F
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.