ArticleOpen heart2021
Characteristics and outcomes of young patients with ST segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: retrospective analysis in a multiethnic Asian population.
Article in Open heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Race and Ethnicity in Cardiovascular Disease Risk Prediction for Multiethnic Populations: Insights From Global Guidelines.JACC. Asia · 2026Review
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- Inflammatory markers guide early risk stratification and prognosis in elderly patients with acute myocardial infarction.Scientific reports · 2025Article
- Risk factors associated with ST-segment elevation myocardial infarctions among young patients treated in the Mid-West of Ireland: a case series report using secondary data.Irish journal of medical science · 2025Article
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- A proposed method for identifying Interfacility transfers in Medicare claims data.Health services research · 2025Observational
- Clinical predictors and outcomes of ST-elevation myocardial infarction related cardiogenic shock in the Asian population.International journal of cardiology. Heart & vasculature · 2024Article
- Impact of Guideline-Directed Drug Therapy after ST-Elevation Myocardial Infarction on Outcome in Young Patients-Age and Sex-Specific Factors.Journal of clinical medicine · 2024Article
- Article
- Clinical Characteristics and Outcomes of Elderly Patients Undergoing Primary Percutaneous Coronary Intervention: An Observational Cohort Study.Global heart · 2024Observational
- Atherosclerotic cardiovascular disease landscape in Singapore.Frontiers in cardiovascular medicine · 2024Review
- Clinical risk factors and outcomes of young patients with acute ST segment elevation myocardial infarction: a retrospective study.BMC cardiovascular disorders · 2023Article
- Pre-hospital delay, clinical characteristics, angiographic findings, and in-hospital mortality in young and middle-aged adults with acute coronary syndrome: a single-centre registry analysis.European heart journal supplements : journal of the European Society of Cardiology · 2023Article
- Characterization of features and outcomes of young patients (< 45 years) presenting with ST-segment elevation myocardial infarction.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023Article
- ST-Elevation Acute Myocardial Infarction in a Young Man.Journal of medical cases · 2022Article
- One-year outcomes of patients with ST-segment elevation myocardial infarction during the COVID-19 pandemic.Journal of thrombosis and thrombolysis · 2022Article
- Acute Myocardial Infarction in Young Men Under 50 Years of Age: Clinical Characteristics, Treatment, and Long-Term Prognosis.International journal of general medicine · 2021Article
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Authors and funding
17 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveST segment elevation myocardial infarction (STEMI) is associated with significant mortality leading to loss of productive life years, especially in younger patients. This study aims to compare the characteristics and outcomes of young versus older patients with STEMI undergoing primary percutaneous coronary intervention (PPCI) to help focus public health efforts in STEMI prevention.
methodsData from the Coronary Care Unit database of the National University Hospital, Singapore from July 2015 to June 2019 were reviewed. Patients were divided into young (<50 years old) or older (≥50 years old) groups.
resultsOf the 1818 consecutive patients with STEMI who underwent PPCI, 465 (25.6%) were <50 years old. Young compared with older patients were more likely to be male, current smokers, of Indian ethnicity, have family history of ischaemic heart disease (IHD) and had lower 1 year mortality (3.4% vs 10.4%, p<0.0001). Although diabetes, hypertension or dyslipidaemia was less common among young patients, the prevalence of having any one of these risk factors was high in the range of 28% to 38%. Age was an independent predictor of mortality in the older but not younger patients with STEMI, and diabetes showed a trend towards mortality in both groups.
conclusionYoung patients with STEMI are more often smokers, of Indian ethnicity and had family history of IHD, although cardiometabolic risk factors are also prevalent. Mortality is lower, but not negligible, among the young patients with STEMI. Public health efforts are needed to reduce the prevalence of these risk factors among the constitutionally susceptible population.
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