Evidence map›Paper›PMID 33441403›Full record

ArticlemSphere2021

OXA-181-Like Carbapenemases in Klebsiella pneumoniae ST14, ST15, ST23, ST48, and ST231 from Septicemic Neonates: Coexistence with NDM-5, Resistome, Transmissibility, and Genome Diversity.

Sharmi Naha, Kirsty Sands, Subhankar Mukherjee, Bijan Saha, Shanta Dutta, Sulagna Basu

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Genomic landscape ofApplied and environmental microbiology · 2026
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  7. Article
  8. Article
  9. Article
  10. Genomic characterization ofFrontiers in microbiology · 2026
    Article
  11. Plasmid genomic epidemiology ofMicrobial genomics · 2025
    Article
  12. Article
  13. Emergence ofAntibiotics (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Carbapenem-resistantJAC-antimicrobial resistance · 2024
    Article
  16. Carbapenem- and colistin-resistantFrontiers in microbiology · 2024
    Article
  17. Article
  18. Article
  19. First Report of OXA-181-ProducingMicrobiology spectrum · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sharmi NahaDivision of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, West Bengal, India.
Kirsty SandsDepartment of Medical Microbiology and Infectious Disease, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, United Kingdom.
Subhankar MukherjeeDivision of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, West Bengal, India.
Bijan SahaDepartment of Neonatology, Institute of Post-Graduate Medical Education & Research and SSKM Hospital, Kolkata, West Bengal, India.
Shanta DuttaDivision of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, West Bengal, India.
Sulagna BasuDivision of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, West Bengal, India basus.niced@gov.in.ORCID 0000-0002-7811-7140
National Institute of Cholera and Enteric Diseases · INCardiff University · GBInstitute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies on the epidemiology and genomes of isolates harboring OXA-48-like genes in septicemic neonates are rare. Here, isolates producing these carbapenemases which emerged and persisted in an Indian neonatal unit were characterized in terms of their resistome, transmissibility, and genome diversity. Antibiotic susceptibility and whole-genome sequencing were carried out. The sequence types, resistome, virulome, mobile genetic elements, and transmissibility of carbapenem-resistant plasmids were evaluated. Core genome analysis of isolates was shown in a global context with other OXA-48-like carbapenemase-harboring genomes, including those from neonatal studies. Eleven OXA-48-like carbapenemase-producing

Indexed as

Genetic VariationGenome, BacterialAnti-Bacterial Agentsbeta-LactamasesGenotypeHumansInfant, NewbornKlebsiella InfectionsKlebsiella pneumoniaeMicrobial Sensitivity TestsMultilocus Sequence TypingNeonatal SepsisTanzaniaWhole Genome SequencingAnti-Bacterial Agentsbeta-lactamase NDM-1beta-LactamasesColKP3core genomedual carbapenemasesIndiaNDM-5neonatesOXA-181/232sepsisWGS

Identifiers

PMID33441403
PMCPMC7845606
OpenAlexW3120899485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.