Evidence map›Paper›PMID 33441339›Full record

ArticleJournal of virology2021

The immunological impact of adenovirus early genes on vaccine-induced responses in mice and nonhuman primates.

Kotou Sangare, Iskra Tuero, Mohammad Arif Rahman, Tanya Hoang, Leia K Miller-Novak, Diego A Vargas-Inchaustegui, David J Venzon, Celia LaBranche, David C Montefiori, Marjorie Robert-Guroff and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. E4orf1 SuppressesVaccines · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Kotou SangareDepartment of Biology, Howard University, Washington, DC, USA.
Iskra TueroSection on Immune Biology of Retroviral Infection, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Mohammad Arif RahmanSection on Immune Biology of Retroviral Infection, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Tanya HoangSection on Immune Biology of Retroviral Infection, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Leia K Miller-NovakSection on Immune Biology of Retroviral Infection, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Diego A Vargas-InchausteguiSection on Immune Biology of Retroviral Infection, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
David J VenzonBiostatistics and Data Management Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-8990-158X
Celia LaBrancheDuke University Medical Center, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0002-6653-6655
David C MontefioriDuke University Medical Center, Durham, North Carolina, USA.
Marjorie Robert-GuroffSection on Immune Biology of Retroviral Infection, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0003-0606-6636
Michael A ThomasDepartment of Biology, Howard University, Washington, DC, USA michael.thomas1@howard.edu.ORCID https://orcid.org/0000-0003-0134-8765
National Institutes of Health · USDuke Medical Center · USHoward University · US

Funding

Office of Collaborative BiostatisticsZIDSC007202 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI CHOO-WOSOBA, HYOYOUNG · 2009 to 2025
$14.5M
Effective Replicating Adenovirus-HIV VaccinesR00AI114379 · NIAID · HOWARD UNIVERSITY · PI THOMAS, MICHAEL A · 2016 to 2017
$498k
NIAID NIH HHS R00 AI114379
6 · The paper itself

Abstract

Adenovirus (Ad) is being explored for use in the prevention and treatment of a variety of infectious diseases and cancers. Ad with a deletion in early region 3 (

Identifiers

PMID33441339
PMCPMC8092689
OpenAlexW3118972956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.