Evidence map›Paper›PMID 33441170›Full record

ArticleVirology journal2021

Cross-sectional retrospective analysis of clinical characteristics of chronic hepatitis B patients with oral antiviral treatment in eastern China.

Jueqing Gu, Guodong Yu, Xiaoli Zhang, Shanyan Zhang, Huan Cai, Chanyuan Ye, Yida Yang, Dezhou Li, Zhaowei Tong, Huajiang Shen and 6 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Virology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Jueqing GuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, 310031, CN, China.
Guodong YuState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, 310031, CN, China.
Xiaoli ZhangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, 310031, CN, China.
Shanyan ZhangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, 310031, CN, China.
Huan CaiState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, 310031, CN, China.
Chanyuan YeState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, 310031, CN, China.
Yida YangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, 310031, CN, China. yidayang65@zju.edu.cn.ORCID 0000-0002-9673-0969
Dezhou LiDepartment of Infectious Diseases, Ningbo No 2 Hospital, Ningbo, China.
Zhaowei TongDepartment of Infectious Diseases, Huzhou Central Hospital, Huzhou, China.
Huajiang ShenDepartment of Infectious Diseases, Affiliated Hospital of Shaoxing University, Shaoxing, China.
Huazhong ChenDepartment of Infectious Diseases, WenZhou Medical College Affiliated Taizhou Hospital, Wenzhou, China.
Feng DingDepartment of Infectious Diseases, Affiliated Hospital of Shaoxing University, Shaoxing, China.
Xijie LaiDepartment of Infectious Diseases, Ningbo No 2 Hospital, Ningbo, China.
Junyan LiuDepartment of Infectious Diseases, WenZhou Medical College Affiliated Taizhou Hospital, Wenzhou, China.
Meiling XuDepartment of Infectious Diseases, Huzhou Central Hospital, Huzhou, China.
Weiti WuDepartment of Infectious Diseases, WenZhou Medical College Affiliated Taizhou Hospital, Wenzhou, China.
State Key Laboratory of Diagnosis and Treatment of Infectious DiseasesWenzhou Medical University · CNHuzhou Central Hospital · CNNingbo No. 2 Hospital · CNShaoxing University · CNNational Clinical Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn China, more than 20 million patients with chronic hepatitis B need antiviral treatment. Side effects of antiviral treatment such as renal complications can be problematic, particularly in an aging population.

methodsThe data were retrospectively extracted from the hospital medical charts of five centers in eastern China from January 1 to December 31, 2018.

resultsA total of 8309 patients with CHB was enrolled in this study. The median age of the patients was 46 years. The prevalence of diabetes mellitus, hypertension, and hepatic cirrhosis was respectively 3.49%, 4.42%, and 23.72%. The prevalence of these comorbidities increased with age (P < 0.001). Of the patients with CHB, 5332 had complete renal function results. Among them, patients with an estimated glomerular filtration rate of < 60 mL/min/1.73m

Indexed as

Administration, OralAdolescentAdultAgedAged, 80 and overAntiviral AgentsCross-Sectional StudiesDrug Therapy, CombinationFemaleHepatitis B, ChronicHumansMaleMiddle AgedPrevalenceRenal Insufficiency, ChronicRetrospective StudiesAntiviral AgentsAgingAntiviral treatmentChronic hepatitis BComorbidity

Identifiers

PMID33441170
PMCPMC7805123
OpenAlexW3118248776

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.