Evidence map›Paper›PMID 33441164›Full record

ArticleJournal of pharmaceutical policy and practice2021

Patterns of infections and antimicrobial drugs' prescribing among pregnant women in Saudi Arabia: a cross sectional study.

Mohamed A Baraka, Lina Hussain AlLehaibi, Hind Nasser AlSuwaidan, Duaa Alsulaiman, Md Ashraful Islam, Badriyah Shadid Alotaibi, Amany Alboghdadly, Ali H Homoud, Fuad H Al-Ghamdi, Mastour S Al Ghamdi and 1 more

Abstract read
In one paragraph

Article in Journal of pharmaceutical policy and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Review
  5. Article
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  8. Review
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  11. Urinary tract infection in women.Przeglad menopauzalny = Menopause review · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohamed A BarakaClinical Pharmacy Department, College of Pharmacy, Al Ain University, Al Ain Campus, Al Ain, United Arab Emirates. mohamed.baraka@aau.ac.ae.ORCID http://orcid.org/0000-0002-7645-2420
Lina Hussain AlLehaibiFirst Health Cluster in Eastern Province, Dammam Medical Complex, Dammam, 32245, Saudi Arabia.
Hind Nasser AlSuwaidanCollege of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, P.O. Box. 1982, Dammam, 31441, Saudi Arabia.
Duaa AlsulaimanKing Fahd Hospital of the University (KFHU), Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Md Ashraful IslamPharmacy Practice Department, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Badriyah Shadid AlotaibiDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Amany AlboghdadlyCollege of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Ali H HomoudClinical Pharmacy Service, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
Fuad H Al-GhamdiPharmacy Department at Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
Mastour S Al GhamdiDepartment of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Zaheer-Ud-Din BabarDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK.

Funding

The Health Sciences Research Center, King Abdullah bin Abdulaziz University Hospital, Princess Nourah bint Abdulrahman University G18-00021
6 · The paper itself

Abstract

backgroundAntimicrobial agents are among the most commonly prescribed drugs in pregnancy due to the increased susceptibility to infections during pregnancy. Antimicrobials can contribute to different maternal complications. Therefore, it is important to study their patterns in prescription and utilization. The data regarding this issue is scarce in Saudi Arabia. Therefore, the aim of this study is to generate data on the antimicrobial agents that are most commonly prescribed during pregnancy as well as their indications and safety.

methodsThis is a retrospective study focusing on pregnant women with a known antimicrobial use at Johns Hopkins Aramco Healthcare (JHAH). The sample included 344 pregnant women with a total of 688 antimicrobial agents prescribed. Data was collected on the proportion of pregnant women who received antimicrobial agents and on the drug safety during pregnancy using the risk categorization system of the U.S. Food and Drug Administration (FDA).

resultsThe results showed that urinary tract infections (UTIs) were the most reported (59%) infectious diseases. Around 48% of pregnant women received antimicrobial medications at some point during pregnancy. The top two antimicrobial agents based on prescription frequency were B-lactams (44.6%) and azole anti-fungals (30%). The prescribed drugs in the study were found to be from classes B, C and D under the FDA risk classification system.

conclusionThe study revealed a high proportion of antimicrobials prescribed during pregnancy that might pose risks to mothers and their fetuses. Future multicenter studies are warranted to evaluate the rational prescription of antimicrobial medications during pregnancy.

Indexed as

AntibioticsAntimicrobial drugsAntimicrobial resistanceAntimicrobial stewardship programsDrug utilization patternInfectionsPregnancySaudi Arabia

Identifiers

PMID33441164
PMCPMC7807808

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.