Evidence map›Paper›PMID 33440918›Full record

ArticleIntestinal research2022

Clinical presentation of COVID-19 in patients with inflammatory bowel disease: a systematic review and meta-analysis.

Anupam K Singh, Anuraag Jena, Praveen Kumar-M, Daya Krishna Jha, Vishal Sharma

Open access · diamondAbstract read
In one paragraph

Article in Intestinal research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  4. Diarrhea and Coronavirus Disease 2019 Infection.Gastroenterology clinics of North America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anupam K SinghDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Anuraag JenaDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Praveen Kumar-MDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Daya Krishna JhaDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Vishal SharmaDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsCoronavirus disease 2019 (COVID-19) is recognized to have variable clinical manifestations. The clinical presentation of patients with inflammatory bowel disease (IBD) having COVID-19 is unclear.

methodsWe identified articles reporting about the clinical presentation of COVID-19 in those with underlying IBD from PubMed and Embase. The studies, irrespective of design or language, were included. The overall pooled frequency of various symptoms was estimated. Joanna Briggs Institute Critical appraisal checklist was used to assess the quality of studies.

resultsEleven studies, including 1,325 patients, were included in the pooled analysis. The pooled estimates for clinical presentation were; fever: 67.53% (95% confidence interval [CI], 45.38-83.88), cough: 59.58% (95% CI, 45.01-72.63), diarrhea: 27.26% (95% CI, 19.51-36.69), running nose: 27% (95% CI, 15.26-43.19) and dyspnea: 25.29% (95% CI, 18.52-33.52). The pooled prevalence rates for abdominal pain, nausea and vomiting were 13.08% (95% CI, 9.24-18.19), 10.08% (95% CI, 5.84-16.85) and 8.80% (95% CI, 4.43-16.70) per 100 population, respectively.

conclusionsThe clinical presentation of COVID-19 in IBD patients is similar to the general population.

Indexed as

CoronavirusCrohn diseaseDiarrheaInflammatory bowel diseaseUlcerative colitis

Identifiers

PMID33440918
PMCPMC8831773
OpenAlexW3120746154

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.