Evidence map›Paper›PMID 33440800›Full record

ReviewAntioxidants (Basel, Switzerland)2021

The Impact of Unbalanced Maternal Nutritional Intakes on Oocyte Mitochondrial Activity: Implications for Reproductive Function.

Gemma Fabozzi, Benedetta Iussig, Danilo Cimadomo, Alberto Vaiarelli, Roberta Maggiulli, Nicolò Ubaldi, Filippo Maria Ubaldi, Laura Rienzi

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Mitochondria Biology in Reproductive Function.Antioxidants (Basel, Switzerland) · 2022
    Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Gemma FabozziClinica Valle Giulia, GeneraLife IVF Centers, 00197 Rome, Italy.ORCID 0000-0002-6224-4997
Benedetta IussigGenera Veneto, GeneraLife IVF Centers, 36063 Marostica, Italy.
Danilo CimadomoClinica Valle Giulia, GeneraLife IVF Centers, 00197 Rome, Italy.ORCID 0000-0002-5390-9221
Alberto VaiarelliClinica Valle Giulia, GeneraLife IVF Centers, 00197 Rome, Italy.
Roberta MaggiulliClinica Valle Giulia, GeneraLife IVF Centers, 00197 Rome, Italy.
Nicolò UbaldiCatholic University of the Sacred Heart, 20123 Rome, Italy.ORCID 0000-0003-1128-4144
Filippo Maria UbaldiClinica Valle Giulia, GeneraLife IVF Centers, 00197 Rome, Italy.
Laura RienziClinica Valle Giulia, GeneraLife IVF Centers, 00197 Rome, Italy.
Regione del Veneto · ITClinica Valle Giulia · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence on the effect of nutrition on reproduction is emerging from both animal and human studies. A healthy dietary pattern and nutrient supplementation, especially during the peri-conceptional period, might be helpful to achieve a live birth, although the mechanisms implicated are not fully understood. The endocrine system and the ooplasmic organelles apparatus, in particular the mitochondria, are clearly key elements during oogenesis and subsequent embryo development, and their proper functioning is associated with nutrition, even beyond maternal aging. Several studies in animal models have reported various adverse effects on mitochondria caused by unbalanced dietary intakes such as high fat diet, high fat high sugar diet, and low protein diet. The alterations produced might include mitochondrial intracellular distribution, content, structure, biogenesis, and functioning. This review summarizes the key role of mitochondria in female reproduction and the effects of different dietary macronutrient compositions on oocyte mitochondrial activity with their possible short-, medium-, and long-term effects.

Indexed as

developmentaldietmitochondrianutritionoocytesreproductive competence

Identifiers

PMID33440800
PMCPMC7826933
OpenAlexW3119019923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.