Evidence map›Paper›PMID 33440758›Full record

ArticleViruses2021

Zika Virus Infection Leads to Demyelination and Axonal Injury in Mature CNS Cultures.

Verena Schultz, Stephanie L Cumberworth, Quan Gu, Natasha Johnson, Claire L Donald, George A McCanney, Jennifer A Barrie, Ana Da Silva Filipe, Christopher Linington, Hugh J Willison and 3 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

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  17. Neurological and neuropsychological sequelae of Zika virus infection in children in León, Nicaragua.Revista panamericana de salud publica = Pan American journal of public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Verena SchultzInstitute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.ORCID 0000-0002-8172-1525
Stephanie L CumberworthMRC-University of Glasgow Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G61 1QH, UK.
Quan GuMRC-University of Glasgow Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G61 1QH, UK.
Natasha JohnsonMRC-University of Glasgow Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G61 1QH, UK.ORCID 0000-0002-4246-6082
Claire L DonaldMRC-University of Glasgow Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G61 1QH, UK.ORCID 0000-0002-4370-0707
George A McCanneyInstitute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
Jennifer A BarrieInstitute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
Ana Da Silva FilipeMRC-University of Glasgow Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G61 1QH, UK.
Christopher LiningtonInstitute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
Hugh J WillisonInstitute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
Julia M EdgarInstitute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
Susan C BarnettInstitute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
Alain KohlMRC-University of Glasgow Centre for Virus Research, Institute of Infection, Immunity and Inflammation, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G61 1QH, UK.
University of Glasgow · GBMRC University of Glasgow Centre for Virus Research · GB

Funding

Medical Research Council MC_PC_15105Medical Research Council MC_UU_12014/12Medical Research Council MC_UU_12014/8Medical Research Council MR/K501335/1Medical Research Council MR/N017552/1Wellcome Trust 203680/Z/16/ZWellcome Trust WT092805
6 · The paper itself

Abstract

Understanding how Zika virus (

Indexed as

AnimalsAxonsBiomarkersCranial Nerve InjuriesDemyelinating DiseasesDisease Models, AnimalGene Expression ProfilingHumansMiceRatsTranscriptomeZika VirusZika Virus InfectionBiomarkersCCL5demyelinationmature CNSZika virus

Identifiers

PMID33440758
PMCPMC7827345
OpenAlexW3108341171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.