Evidence map›Paper›PMID 33440647›Full record

ArticleInternational journal of environmental research and public health2021

In Vitro and In Vivo Evaluation of Nanostructured Biphasic Calcium Phosphate in Granules and Putty Configurations.

Jhonathan R B Nascimento, Suelen C Sartoretto, Adriana T N N Alves, Carlos F A B Mourão, Victor R Martinez-Zelaya, Marcelo J Uzeda, José M Granjeiro, Pietro Montemezzi, Monica D Calasans-Maia, José A Calasans-Maia

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Jhonathan R B NascimentoGraduate Program, Dentistry School, Universidade Federal Fluminense, Niteroi 24020-140, Brazil.
Suelen C SartorettoOral Surgery Department, Dentistry School, Universidade Veiga de Almeida, Rio de Janeiro 20271-020, Brazil.ORCID 0000-0002-8414-3775
Adriana T N N AlvesOral Diagnosis Department, Dentistry School, Universidade Federal Fluminense, Niteroi 24020-140, Brazil.
Carlos F A B MourãoGraduate Program, Dentistry School, Universidade Federal Fluminense, Niteroi 24020-140, Brazil.ORCID 0000-0001-5775-0222
Victor R Martinez-ZelayaBrazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas 13083-100, Brazil.ORCID 0000-0001-5256-2919
Marcelo J UzedaOral Surgery Department, Dentistry School, Universidade Iguaçu, Nova Iguaçu 26260-045, Brazil.ORCID 0000-0001-9148-9929
José M GranjeiroDirectory of Life Sciences Applied Metrology, Instituto Nacional de Metrologia, Qualidade e Tecnologia (INMETRO), Duque de Caxias 25250-020, Brazil.
Pietro MontemezziPrivate Practice, 24121 Bergamo, Italy.
Monica D Calasans-MaiaOral Surgery Department, Universidade Federal Fluminense, Niteroi 24020-140, Brazil.ORCID 0000-0001-5759-7926
José A Calasans-MaiaOrthodontics Department, Universidade Federal Fluminense, Niteroi 24020-140, Brazil.ORCID 0000-0002-1498-726X
Universidade Federal Fluminense · BRBrazilian Synchrotron Light Laboratory · BRUniversidade Iguaçu · BRUniversity of Bergamo · IT

Funding

Lacrimal Gland Repair Using Progenitor CellsR01EY026202 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI MAKARENKOVA, HELEN P. · 2016 to 2025
$5.2M
6 · The paper itself

Abstract

Synthetic biphasic calcium phosphate (BCP) granules and powder are biocompatible biomaterials with a well-known capacity for osteoconduction, presenting very satisfactory clinical and histological results. It remains unanswered if the putty configuration impacts the biological response to the material. In this study, we aimed to compare the cytocompatibility and biocompatibility of nanostructured BCP in the putty configuration (moldable nanostructured calcium phosphate, MnCaP) on the healing of critical-sized bone defects (8 mm) in rat calvaria. Cytocompatibility was determined through the viability of fibroblast cells (V-79) to the extracts of different concentrations of MnCaP. Forty-five Wistar rats were randomly divided into three groups (

Indexed as

Bone SubstitutesAnimalsBone RegenerationHydroxyapatitesRatsRats, WistarBone Substituteshydroxyapatite-beta tricalcium phosphateHydroxyapatitesbiocompatibilitybiomaterialcytocompatibilitymicrotomography

Identifiers

PMID33440647
PMCPMC7826908
OpenAlexW3119353394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.