Evidence map›Paper›PMID 33440628›Full record

ArticleMarine drugs2021

Engineering Bafilomycin High-Producers by Manipulating Regulatory and Biosynthetic Genes in the Marine Bacterium

Zhong Li, Shuai Li, Lei Du, Xingwang Zhang, Yuanyuan Jiang, Wenhua Liu, Wei Zhang, Shengying Li

Abstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhong LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Shuai LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Lei DuState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.ORCID 0000-0003-2245-7100
Xingwang ZhangState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Yuanyuan JiangState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Wenhua LiuState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Wei ZhangState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.
Shengying LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.ORCID 0000-0002-5244-870X

Funding

National Key Research and Development Program of China 2019YFA0905704 and 2019YFA0905100National Natural Science Foundation of China 32025001, 82022066, 81741155 and 32000039Shandong Provincial Natural Science Foundation ZR2019ZD20The Laboratory for Marine Drugs and Bioproducts of Pilot National Laboratory for Marine Science and Technology (Qingdao) LMDBKF-2019-01The State Key Laboratory of Bio-organic and Natural Products Chemistry SKLBNPC18242Weihai Science and Technology Development Program 2018ZC11
6 · The paper itself

Abstract

Bafilomycin A

Indexed as

Aquatic OrganismsGene Knockout TechniquesGenetic EngineeringMacrolidesProtein BiosynthesisStreptomycesMacrolidesbafilomycinbiosynthesisfermentation optimizationregulatory geneStreptomyces

Identifiers

PMID33440628
PMCPMC7827423

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.