Evidence map›Paper›PMID 33440601›Full record

ArticleCells2021

Role of Annexin A1 in NLRP3 Inflammasome Activation in Murine Neutrophils.

José Marcos Sanches, Rebeca D Correia-Silva, Gustavo H B Duarte, Anna Maria A P Fernandes, Salvador Sánchez-Vinces, Patrícia O Carvalho, Sonia M Oliani, Karina R Bortoluci, Vanessa Moreira, Cristiane D Gil

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. AcCells · 2025
    Article
  3. Article
  4. Article
  5. Poststroke venous thromboembolism and neutrophil activation: an illustrated review.Research and practice in thrombosis and haemostasis · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

José Marcos SanchesPrograma de Pós-Graduação em Biologia Estrutural e Funcional, Universidade Federal de São Paulo, São Paulo 04023-900, Brazil.
Rebeca D Correia-SilvaPrograma de Pós-Graduação em Biologia Estrutural e Funcional, Universidade Federal de São Paulo, São Paulo 04023-900, Brazil.
Gustavo H B DuarteInstituto de Química, Universidade Estadual de Campinas, Campinas 13083-862, São Paulo, Brazil.
Anna Maria A P FernandesLaboratório de Pesquisa Multidisciplinar, Universidade São Francisco, Bragança Paulista 12916-900, São Paulo, Brazil.ORCID 0000-0002-4285-3656
Salvador Sánchez-VincesLaboratório de Pesquisa Multidisciplinar, Universidade São Francisco, Bragança Paulista 12916-900, São Paulo, Brazil.ORCID 0000-0001-7041-6544
Patrícia O CarvalhoLaboratório de Pesquisa Multidisciplinar, Universidade São Francisco, Bragança Paulista 12916-900, São Paulo, Brazil.ORCID 0000-0002-2681-7022
Sonia M OlianiPrograma de Pós-Graduação em Biologia Estrutural e Funcional, Universidade Federal de São Paulo, São Paulo 04023-900, Brazil.
Karina R BortoluciDepartamento de Ciências Biológicas e Centro de Terapia Celular e Molecular, Universidade Federal de São Paulo, São Paulo 04044-010, Brazil.
Vanessa MoreiraDepartamento de Farmacologia, Universidade Federal de São Paulo, São Paulo 04044-020, Brazil.ORCID 0000-0002-4048-1967
Cristiane D GilPrograma de Pós-Graduação em Biologia Estrutural e Funcional, Universidade Federal de São Paulo, São Paulo 04023-900, Brazil.ORCID 0000-0001-6979-4126
Universidade Federal de São Paulo · BRUniversidade São Francisco · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the role of endogenous and exogenous annexin A1 (AnxA1) in the activation of the NLRP3 inflammasome in isolated peritoneal neutrophils. C57BL/6 wild-type (WT) and AnxA1 knockout mice (AnxA1

Indexed as

AnimalsAnnexin A1InflammasomesInterleukin-1betaLipidsMaleMiceMice, Inbred C57BLNeutrophil ActivationNeutrophilsNLR Family, Pyrin Domain-Containing 3 ProteinAnnexin A1InflammasomesInterleukin-1betaLipidsNLR Family, Pyrin Domain-Containing 3 ProteinAc2-26ATPinflammationlipidomicsmass spectrometrynigericin

Identifiers

PMID33440601
PMCPMC7827236
OpenAlexW3120637705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.