Evidence map›Paper›PMID 33440138›Full record

ArticleImmunity2021

IL-33 Changes Our "Gut Feelings" about Serotonin.

Lewis W Yu, Elaine Y Hsiao

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lewis W YuDepartment of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Elaine Y HsiaoDepartment of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: ehsiao@g.ucla.edu.
University of California, Los Angeles · US

Funding

Functional Role of IL-6 in Fetal Brain Development and Abnormal BehaviorF31MH090749 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HSIAO, ELAINE · 2011 to 2012
$64k
NIMH NIH HHS F31 MH090749
6 · The paper itself

Abstract

Many studies highlight direct interactions between immune cells and enteric neurons, but whether immune signals can indirectly modulate enteric function through neurotransmitter regulation is poorly understood. In this issue of Immunity, Chen et al. reveal how IL-33 induces intestinal serotonin to promote gut motility.

Indexed as

Interleukin-33SerotoninEmotionsIntestine, SmallNeuronsInterleukin-33Serotonin

Identifiers

PMID33440138
OpenAlexW3119895144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.