ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021
The impact of ventilation-perfusion inequality in COVID-19: a computational model.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparison between high-flow nasal cannula and conventional oxygen therapy in COVID-19 patients: a systematic review and meta-analysis.Therapeutic advances in respiratory diseasePooled it
- Coupled mixed-dimensional multiphase porous media approach for modeling airflow, blood flow, and gas exchange in the human lungs.Biomechanics and modeling in mechanobiology · 2026Article
- Quantitative Computed Tomography and Response to Pronation in COVID-19 ARDS.Respiratory care · 2024Observational
- Oscillometry Longitudinal Data on COVID-19 Acute Respiratory Syndrome Treated with Non-Invasive Respiratory Support.Journal of clinical medicine · 2024Article
- Single-FiOJournal of clinical monitoring and computing · 2023Article
- Association of carbon monoxide poisonings and carboxyhemoglobin levels with COVID-19 and clinical severity.World journal of methodology · 2023Article
- Regional lung perfusion using different indicators in electrical impedance tomography.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Machine learning with multimodal data for COVID-19.Heliyon · 2023Review
- Lung Recruitment Assessed by Electrical Impedance Tomography (RECRUIT): A Multicenter Study of COVID-19 Acute Respiratory Distress Syndrome.American journal of respiratory and critical care medicine · 2023Article
- Article
- Pathophysiology of Hypoxemia in COVID-19 Lung Disease.Clinics in chest medicine · 2023Review
- Mechanical Power Ratio and Respiratory Treatment Escalation in COVID-19 Pneumonia: A Secondary Analysis of a Prospectively Enrolled Cohort.Anesthesiology · 2023Article
- Awake Prone Positioning for Non-Intubated COVID-19 Patients with Acute Respiratory Failure: A Meta-Analysis of Randomised Controlled Trials.Journal of clinical medicine · 2023Review
- Physiologic Effects of the Awake Prone Position Combined With High-Flow Nasal Oxygen on Gas Exchange and Work of Breathing in Patients With Severe COVID-19 Pneumonia: A Randomized Crossover Trial.Critical care explorations · 2022Article
- Chest dual-energy CT to assess the effects of steroids on lung function in severe COVID-19 patients.Critical care (London, England) · 2022Observational
- Hypoxaemia in the early stage of COVID-19: prevalence of physical or biochemical factors?European respiratory review : an official journal of the European Respiratory Society · 2022Article
- Silent Hypoxemia in the Emergency Department: A Retrospective Cohort of Two Clinical Phenotypes in Critical COVID-19.Journal of clinical medicine · 2022Article
- Extent and Distribution of Parenchymal Abnormalities in Baseline CT-Scans Do Not Predict Awake Prone Positioning Response in COVID-19 Related ARDS.Diagnostics (Basel, Switzerland) · 2022Article
- Early versus late intubation in COVID-19 patients failing helmet CPAP: A quantitative computed tomography study.Respiratory physiology & neurobiology · 2022Article
- Mechanical ventilation in COVID-19: A physiological perspective.Experimental physiology · 2022Review
Corrections and comments
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
COVID-19 infection may lead to acute respiratory distress syndrome (CARDS) where severe gas exchange derangements may be associated, at least in the early stages, only with minor pulmonary infiltrates. This may suggest that the shunt associated to the gasless lung parenchyma is not sufficient to explain CARDS hypoxemia. We designed an algorithm (Vent
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.