Evidence map›Paper›PMID 33439735›Full record

ArticleHypertension (Dallas, Tex. : 1979)2021

Butyrate Regulates COVID-19-Relevant Genes in Gut Epithelial Organoids From Normotensive Rats.

Jing Li, Elaine M Richards, Eileen M Handberg, Carl J Pepine, Mohan K Raizada

Open access · greenAbstract readLetterComment
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
1.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 66 citations in OpenAlex.

  1. Observational
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  3. The role ofFrontiers in immunology · 2026
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  8. Role of short-chain fatty acids in host physiology.Animal models and experimental medicine · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jing LiFrom the Department of Physiology and Functional Genomics (J.L., E.M.R., M.K.R.), University of Florida College of Medicine, Gainesville, Florida.
Elaine M RichardsFrom the Department of Physiology and Functional Genomics (J.L., E.M.R., M.K.R.), University of Florida College of Medicine, Gainesville, Florida.
Eileen M HandbergDivision of Cardiovascular Medicine, Department of Medicine (E.M.H., C.J.P.), University of Florida College of Medicine, Gainesville, Florida.
Carl J PepineDivision of Cardiovascular Medicine, Department of Medicine (E.M.H., C.J.P.), University of Florida College of Medicine, Gainesville, Florida.
Mohan K RaizadaFrom the Department of Physiology and Functional Genomics (J.L., E.M.R., M.K.R.), University of Florida College of Medicine, Gainesville, Florida.
University of Florida · USFlorida College · US

Funding

Brain Angiotensin In Hypertensive Neurons in CultureR37HL033610 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K. · 2003 to 2012
$5.8M
Brain-Gut Microbiome-Immune Axis in HypertensionR01HL132448 · NHLBI · UNIVERSITY OF FLORIDA · PI Carl J Pepine, Steven Michael Smith · 2016 to 2026
$4.5M
BRAIN ANGIOTENSIN IN HYPERTENSIVE NEURONS IN CULTURER01HL033610 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K., SUMNERS, COLIN · 1985 to 2017
$4.3M
Angiotensin-Converting Enzyme2 in Vascular Endothelial FunctionR01HL102033 · NHLBI · UNIVERSITY OF FLORIDA · PI RAIZADA, MOHAN K. · 2010 to 2019
$4.3M
Vascular Reparative Mechanism by ACE2/Ang-(1-7)in DiabetesR01HL110170 · NHLBI · UNIVERSITY OF FLORIDA · PI GRANT, MARIA BARTOLOMEO · 2011 to 2015
$2.2M
NHLBI NIH HHS R01 HL033610NHLBI NIH HHS R01 HL102033NHLBI NIH HHS R01 HL110170NHLBI NIH HHS R01 HL132448NHLBI NIH HHS R37 HL033610
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Gastrointestinal MicrobiomeAngiotensin-Converting Enzyme 2AnimalsButyratesHumansOrganoidsPeptidyl-Dipeptidase ARatsSARS-CoV-2Angiotensin-Converting Enzyme 2ButyratesPeptidyl-Dipeptidase A

Identifiers

PMID33439735
PMCPMC7810239
OpenAlexW3108450419

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.