Evidence map›Paper›PMID 33439671›Full record

ArticleMolecular biology of the cell2021

Spatial variation of microtubule depolymerization in large asters.

Keisuke Ishihara, Franziska Decker, Paulo Caldas, James F Pelletier, Martin Loose, Jan Brugués, Timothy J Mitchison

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Self-Organization of Cellular Units.Annual review of cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Keisuke IshiharaMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Franziska DeckerMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Paulo CaldasInstitute of Science and Technology Austria, 3400 Klosterneuburg, Austria.
James F PelletierDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115.
Martin LooseInstitute of Science and Technology Austria, 3400 Klosterneuburg, Austria.
Jan BruguésMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Timothy J MitchisonDepartment of Systems Biology, Harvard Medical School, Boston, MA 02115.
Max Planck Institute for the Physics of Complex Systems · DEInstitute of Science and Technology Austria · ATMarine Biological Laboratory · US

Funding

Cell and Chemical Biology of MicrotubulesR35GM131753 · NIGMS · HARVARD MEDICAL SCHOOL · PI Timothy J Mitchison · 2019 to 2026
$6.4M
NEUROTRANSMITTER RECEPTORSK05DA000074 · NIDA · JOHNS HOPKINS UNIVERSITY · PI SNYDER, SOLOMON H. · 1985 to 2009
$1.3M
NIDA NIH HHS K05 DA000074NIGMS NIH HHS R35 GM131753
6 · The paper itself

Abstract

Microtubule plus-end depolymerization rate is a potentially important target of physiological regulation, but it has been challenging to measure, so its role in spatial organization is poorly understood. Here we apply a method for tracking plus ends based on time difference imaging to measure depolymerization rates in large interphase asters growing in

Indexed as

Actin Depolymerizing FactorsActinsAnimalsInterphaseKinesinsMicroscopy, FluorescenceMicrotubulesSpatio-Temporal AnalysisSpindle ApparatusTubulinXenopus laevisActin Depolymerizing FactorsActinsKinesinsTubulin

Identifiers

PMID33439671
PMCPMC8108532
OpenAlexW3120053759

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.