Evidence map›Paper›PMID 33439522›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2021

Beyond the Isoprene Pattern: Bifunctional Polyene Cyclizations.

Julian M Feilner, Franz-Lucas Haut, Thomas Magauer

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. InIChemical science · 2022
    Article
  5. Programmed Polyene Cyclization Enabled by Chromophore Disruption.Journal of the American Chemical Society · 2022
    Article
  6. Bifunctional Polyene Cyclizations: Synthetic Studies on Pimarane Natural Products.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
  7. Beyond the Isoprene Pattern: Bifunctional Polyene Cyclizations.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julian M FeilnerInstitute of Organic Chemistry and Center for Molecular Biosciences, Leopold-Franzens-University Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.ORCID http://orcid.org/0000-0002-6101-0523
Franz-Lucas HautInstitute of Organic Chemistry and Center for Molecular Biosciences, Leopold-Franzens-University Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.ORCID http://orcid.org/0000-0003-2091-6270
Thomas MagauerInstitute of Organic Chemistry and Center for Molecular Biosciences, Leopold-Franzens-University Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.ORCID http://orcid.org/0000-0003-1290-9556

Funding

Austrian Science Fund (FWF) P31023-NBLAustrian Science Fund FWF P 31023Tyrolean Science Fund (TWF) F.16646/5-2019Tyrolean Science Fund (TWF) UNI-0404/2340
6 · The paper itself

Abstract

Polyene cyclizations are capable of producing molecular complexity in a single step. While classical systems are limited to simple alkyl substitution patterns only, bifunctional polyenes take advantage of the unique reactivity of higher-functionalized alkenes. Here, we highlight the potential of these variants for the synthesis of structurally complex polycycles involving unprecedented termination steps. We also want to provide a stimulus for the development of novel modes of cyclization that involve bifunctional units to enable efficient synthesis of yet inaccessible natural products.

Indexed as

cationic cascadesnatural productspolyene cyclizationterpenoidstotal synthesis

Identifiers

PMID33439522
PMCPMC8336571

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.