Evidence map›Paper›PMID 33439514›Full record

ArticleJournal of cellular and molecular medicine2021

Piezo type mechanosensitive ion channel component 1 facilitates gastric cancer omentum metastasis.

Xiaofei Wang, Guang Cheng, Yu Miao, Fangyuan Qiu, Lugen Bai, Zhongfei Gao, Yunning Huang, Liru Dong, Xing Niu, Xin Wang and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 80 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Piezo channels in tumors.Journal of cancer research and clinical oncology · 2026
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Two Faces of Greater Omentum.Comprehensive physiology · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Role of mechanosensitive channel Piezo1 protein in intestinal inflammation regulation: A potential target.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Xiaofei WangDepartment of Pathology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
Guang ChengCentral Laboratory of Clinical Medical College, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
Yu MiaoDepartment of GI Medicine, General Hospital of Ningxia Medical University, Yinchuan, China.
Fangyuan QiuDepartment of Medical, Jining Second People's Hospital, Jining, China.
Lugen BaiDepartment of laboratory, Jingbian County People's Hospital, Yulin, China.
Zhongfei GaoDepartment of Medical, Jining First People's Hospital, Jining, China.
Yunning HuangDepartment of Gastrointestinal Surgery, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, Ningxia, China.
Liru DongDepartment of Pathology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
Xing NiuDepartment of Second Clinical College, Shengjing Hospital Affiliated to China Medical University, Shenyang, Liaoning, China.
Xin WangDepartment of Pathology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
Yuyang LiDepartment of Pathology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
Hui TangDepartment of Pathology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.
Yuanyi XuDepartment of Pathology, Ningxia Medical University, Yinchuan, China.
Xudong SongDepartment of Pathology, North China University of Science and Technology Affiliated Hospital, Tangshan, China.ORCID 0000-0003-4261-4732
North China University of Science and Technology Affiliated Hospital · CNNingxia Medical University · CNChina Medical University · CNJingning County People's Hospital · CNJining First People's Hospital · CNThe Fourth People's Hospital of Ningxia Hui Autonomous Region · CNXian Yang Central Hospital · CN

Funding

Key R & D plan of the autonomous region in 2018 2018BEG03010Key R & D plan of the autonomous region in 2019 2019BEG03007Project of Hebei Medical Science Research Project 20191127Project of training excellent clinical medical talents and basic research project funded by the government 361036
6 · The paper itself

Abstract

The peritoneum, especially the omentum, is a common site for gastric cancer (GC) metastasis. Our aim was to expound the role and mechanisms of Piezo1 on GC omentum metastasis. A series of functional assays were performed to examine cell proliferation, clone formation, apoptosis, Ca

Indexed as

Gene Expression Regulation, NeoplasticMechanotransduction, CellularAdultAgedAnimalsApoptosisCell Line, TumorCell MovementCell ProliferationDisease Models, AnimalEpithelial-Mesenchymal TransitionFemaleGene Knockdown TechniquesHumansImmunohistochemistryImmunophenotypingIon ChannelsPIEZO1 protein, humanCa2+ influxgastric cancerHIF-1αmigrationomentum metastasisPiezo1

Identifiers

PMID33439514
PMCPMC7882944
OpenAlexW3118748032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.