Evidence map›Paper›PMID 33439092›Full record

ArticleGut microbes

Investigation of a monoclonal antibody against enterotoxigenic

Audrey Y-H Teh, Lisa Cavacini, Yue Hu, Ozan S Kumru, Jian Xiong, David T Bolick, Sangeeta B Joshi, Clemens Grünwald-Gruber, Friedrich Altmann, Mark Klempner and 4 more

Abstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Stability Engineering of Recombinant Secretory IgA.International journal of molecular sciences · 2024
    Article
  7. Review
  8. Recombinant neutralizing secretory IgA antibodies for preventing mucosal acquisition and transmission of SARS-CoV-2.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  9. Article
  10. Shigella-Controlled Human Infection Models: Current and Future Perspectives.Current topics in microbiology and immunology · 2024
    Review
  11. Article
  12. Article
  13. Plant-based biopharmaceutical engineering.Nature reviews bioengineering · 2023
    Review
  14. Article
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Audrey Y-H TehMolecular Immunology Unit, Institute for Infection and Immunity, St. George's University of London, London , UK.
Lisa CavaciniMassBiologics of the University of Massachusetts Medical School , Boston, MA, USA.
Yue HuVaccine Analytics and Formulation Center, Department of Pharmaceutical Chemistry, University of Kansas , Lawrence, KS, USA.
Ozan S KumruVaccine Analytics and Formulation Center, Department of Pharmaceutical Chemistry, University of Kansas , Lawrence, KS, USA.
Jian XiongVaccine Analytics and Formulation Center, Department of Pharmaceutical Chemistry, University of Kansas , Lawrence, KS, USA.
David T BolickDivision of Infectious Disease and International Health, University of Virginia School of Medicine , Charlottesville, VA, USA.ORCID 0000-0001-9281-085X
Sangeeta B JoshiVaccine Analytics and Formulation Center, Department of Pharmaceutical Chemistry, University of Kansas , Lawrence, KS, USA.
Clemens Grünwald-GruberDepartment for Chemistry, Division of Biochemistry, Universität Für Bodenkultur Wien , Vienna, Austria.
Friedrich AltmannDepartment for Chemistry, Division of Biochemistry, Universität Für Bodenkultur Wien , Vienna, Austria.
Mark KlempnerMassBiologics of the University of Massachusetts Medical School , Boston, MA, USA.
Richard L GuerrantDivision of Infectious Disease and International Health, University of Virginia School of Medicine , Charlottesville, VA, USA.
David B VolkinVaccine Analytics and Formulation Center, Department of Pharmaceutical Chemistry, University of Kansas , Lawrence, KS, USA.
Yang WangMassBiologics of the University of Massachusetts Medical School , Boston, MA, USA.
Julian K-C MaMolecular Immunology Unit, Institute for Infection and Immunity, St. George's University of London, London , UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Passive immunization with antibodies is a promising approach against enterotoxigenic

Indexed as

AnimalsAntibodies, BacterialAntibodies, MonoclonalAntibody AffinityBacterial AdhesionCaco-2 CellsEnterotoxigenic Escherichia coliEscherichia coli InfectionsGastric AcidGlycosylationHumansImmunoglobulin A, SecretoryImmunotherapyMiceNicotianaPlants, Genetically ModifiedAntibodies, BacterialAntibodies, MonoclonalImmunoglobulin A, SecretoryEnterotoxigenic Escherichia coliimmunotherapymonoclonal antibodyNicotiana benthamianapassive immunizationsecretory IgA

Identifiers

PMID33439092
PMCPMC7833773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.