ArticleSocial cognitive and affective neuroscience2021
Reported maternal childhood maltreatment experiences, amygdala activation and functional connectivity to infant cry.
Article in Social cognitive and affective neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Neural Correlates of Maternal Posttraumatic Stress in the First Postpartum Year: Blunted Salience and Prefrontal Responses to Infant Distress.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Maladaptive mother-child interactions in mothers with remitted major depression are associated with blunted amygdala responses to child affective facial expressions.Psychological medicine · 2025Article
- Birthing parents' neural response to infant cry: moderating effects of oxytocin and perceived childhood care.Social cognitive and affective neuroscience · 2025Article
- Maternal cortisol concentration is associated with reduced brain activation to infant cry and more intrusive parenting behavior.Psychoneuroendocrinology · 2025Article
- Toward a multi-level approach to the study of the intergenerational transmission of trauma: Current findings and future directions.Development and psychopathology · 2024Review
- Maternal History of Childhood Maltreatment and Brain Responses to Infant Cues Across the Postpartum Period.Child maltreatment · 2024Article
- Trait coping styles and the maternal neural and behavioral sensitivity to an infant.Scientific reports · 2022Article
- Neurobiological Implications of Parent-Child Emotional Availability: A Review.Brain sciences · 2021Review
- Reduced Child-Oriented Face Mirroring Brain Responses in Mothers With Opioid Use Disorder: An Exploratory Study.Frontiers in psychology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Maternal childhood maltreatment experiences (CMEs) may influence responses to infants and affect child outcomes. We examined associations between CME and mothers' neural responses and functional connectivity to infant distress. We hypothesized that mothers with greater CME would exhibit higher amygdala reactivity and amygdala-supplementary motor area (SMA) functional connectivity to own infant's cries. Postpartum mothers (N = 57) assessed for CME completed an functional magnetic resonance imaging task with cry and white-noise stimuli. Amygdala region-of-interest and psychophysiological interaction analyses were performed. Our models tested associations of CME with activation and connectivity during task conditions (own/other and cry/noise). Exploratory analyses with parenting behaviors were performed. Mothers with higher CME exhibited higher amygdala activation to own baby's cries vs other stimuli (F1,392 = 6.9, P < 0.01, N = 57) and higher differential connectivity to cry vs noise between amygdala and SMA (F1,165 = 22.3, P < 0.001). Exploratory analyses revealed positive associations between both amygdala activation and connectivity and maternal non-intrusiveness (Ps < 0.05). Increased amygdala activation to own infant's cry and higher amygdala-SMA functional connectivity suggest motor responses to baby's distress. These findings were associated with less intrusive maternal behaviors. Follow-up studies might replicate these findings, add more granular parenting assessments and explore how cue processing leads to a motivated maternal approach in clinical populations.
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