Evidence map›Paper›PMID 33438182›Full record

ReviewCardiology journal2022

The progress of pulmonary artery denervation.

Yonghui Xie, Na Liu, Zhenghui Xiao, Fang Yang, Yunhong Zeng, Zhou Yang, Yuanxi Xia, Zhi Chen, Yunbin Xiao

Open access · goldAbstract readReview
In one paragraph

Review in Cardiology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yonghui XieAcademy of Pediatrics, University of South China, Changsha, China.
Na LiuDepartment of Cardiology, The Second Xiangya Hospital of Central South University, China.
Zhenghui XiaoAcademy of Pediatrics, University of South China, Changsha, China.
Fang YangDepartment of Cardiology, The Second Xiangya Hospital of Central South University, China.
Yunhong ZengAcademy of Pediatrics, University of South China, Changsha, China.
Zhou YangAcademy of Pediatrics, University of South China, Changsha, China.
Yuanxi XiaAcademy of Pediatrics, University of South China, Changsha, China.
Zhi ChenAcademy of Pediatrics, University of South China, Changsha, China.
Yunbin XiaoAcademy of Pediatrics, University of South China, Changsha, China. xiaoyunbinrui@126.com.ORCID 0000-0003-0208-6947
University of South China · CNHunan Children's Hospital · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH) is a chronic pulmonary vascular disease characterized by increased pulmonary arterial pressure and pulmonary arterioles remodeling. Some studies have discovered the relationship between sympathetic nerves (SNs) and pathogenesis of PAH. This review is aimed to illustrate the location and components of SNs in the pulmonary artery, along with different methods and effects of pulmonary artery denervation (PADN). Studies have shown that the SNs distributed mainly around the main pulmonary artery and pulmonary artery bifurcation. And the SNs could be destroyed by three ways: the chemical way, the surgical way and the catheter-based way. PADN can significantly decrease pulmonary arterial pressure rapidly, improve hemodynamic varieties, and then palliate PAH. PADN has been recognized as a prospective and effective therapy for PAH patients, especially for those with medication-refractory PAH. However, further enlarged clinical studies are needed to confirm accurate distribution of SNs in the pulmonary artery and the efficacy of PADN.

Indexed as

Hypertension, PulmonaryPulmonary Arterial HypertensionHumansProspective StudiesPulmonary ArterySympathectomypulmonary arterial hypertensionpulmonary artery denervationsympathetic nerves

Identifiers

PMID33438182
PMCPMC9170319
OpenAlexW3116105533

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.