Evidence map›Paper›PMID 33438082›Full record

ReviewMolecular biology reports2021

Acute lymphoid leukemia etiopathogenesis.

Thiago Cezar Fujita, Nathália Sousa-Pereira, Marla Karine Amarante, Maria Angelica Ehara Watanabe

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06160115 (The Role of Natural Killer Cell Profiling in Predictions of Blood Stream Infection and Antibiotic Resistance in Acute Lymphoblastic Leukemia Patients Post Chemotherapy.), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06160115 unknown statusnot on this mapstarted 2024, after this paper: background citation

The Role of Natural Killer Cell Profiling in Predictions of Blood Stream Infection and Antibiotic Resistance in Acute Lymphoblastic Leukemia Patients Post Chemotherapy.

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled56ConditionsAcute Lymphoblastic Leukemia, Bloodstream InfectionArmsFlow cytometry
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Can CD34Frontiers in pediatrics · 2023
    Review
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  16. Role ofOncology letters · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thiago Cezar FujitaLaboratory of DNA Polymorphisms and Immunology, Department of Pathological Sciences, Biological Sciences Center, Londrina State University, Londrina, PR, Brazil.
Nathália Sousa-PereiraLaboratory of DNA Polymorphisms and Immunology, Department of Pathological Sciences, Biological Sciences Center, Londrina State University, Londrina, PR, Brazil.
Marla Karine AmaranteLaboratory of DNA Polymorphisms and Immunology, Department of Pathological Sciences, Biological Sciences Center, Londrina State University, Londrina, PR, Brazil. marla@uel.com.ORCID http://orcid.org/0000-0001-8218-8518
Maria Angelica Ehara WatanabeLaboratory of DNA Polymorphisms and Immunology, Department of Pathological Sciences, Biological Sciences Center, Londrina State University, Londrina, PR, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lymphoid leukemia (ALL) is a type of hematological neoplasm that affects the precursor cells of strains B, T  and NK, with a higher incidence in the pediatric range. The pathophysiology of ALL is characterized by chromosomal abnormalities and genetic alterations involved in the differentiation and proliferation of lymphoid precursor cells. Despite the lack of information in the literature, it is believed that leukemogenesis originates from a complex interaction between environmental and genetic factors, which combined lead to cellular modifications. Environmental factors have been evaluated as possible predisposing factors in the development of ALL but there are still conflicting results in the world literature. In this context, the aim of the present review is to discuss the major exogenous factors regarding ALL.

Indexed as

Gene-Environment InteractionAdultB-LymphocytesCarcinogenesisCell DifferentiationCell ProliferationChildChromosome AberrationsCytokinesGene Expression Regulation, LeukemicHumansKiller Cells, NaturalLymphoid Progenitor CellsNeoplasm ProteinsPrecursor Cell Lymphoblastic Leukemia-LymphomaT-LymphocytesCytokinesNeoplasm ProteinsChildhoodEnvironmentInfectionLeukemia

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.