ReviewBMJ paediatrics open2020
Informed consent for neonatal trials: practical points to consider and a check list.
Review in BMJ paediatrics open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Parent and practitioner experiences of opt-out consent in neonatal intensive care: a mixed methods study within a trial.Archives of disease in childhood. Fetal and neonatal edition · 2026Trial
- Development and Preliminary Evaluation of a Questionnaire on Parental Informed Consent in Neonatal Research.Children (Basel, Switzerland) · 2026Article
- The Impact of Opt-In versus Opt-Out Consent Process for the Use of Donor Human Milk on Feeding Practice and Growth Pattern in Preterm Neonates.American journal of perinatology · 2026Article
- Human artificial placenta technology-trials: counselling and informed consent using healthcare professionals' and parental perspectives.Pediatric research · 2025Article
- Design and implementation of a Neonatal Family Research Advisory Council (NFRAC).Journal of perinatology : official journal of the California Perinatal Association · 2025Article
- Parental impact during and after neonatal intensive care admission.Seminars in perinatology · 2024Review
- Parental perceptions of informed consent in a study of tracheal intubations in neonatal intensive care.Frontiers in pediatrics · 2023Article
- Analysis of Paediatric Clinical Trial Characteristics and Activity Over 23 Years-Impact of the European Paediatric Regulation on a Single French Clinical Research Center.Frontiers in pediatrics · 2022Article
- Parental and professional perceptions of informed consent and participation in a time-critical neonatal trial: a mixed-methods study in India, Sri Lanka and Bangladesh.BMJ global health · 2021Article
- Clinical Research in Neonates: Redesigning the Informed Consent Process in the Digital Era.Frontiers in pediatrics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obtaining informed consent from parents of critically ill neonates can be challenging. The parental decision-making process is influenced by the severity of the child's condition, the benefit-risk balance, their emotional state and the quality of the relationship with the clinical team. Independent of local legislation, parents may prefer that consent is sought from both. Misconceptions about the absence of risks or unrealistic expectations about benefits should be openly addressed to avoid misunderstandings which may harm the relationship with the clinical team. Continuous consent can be sought where it is unclear whether the free choice of parental consent has been compromised. Obtaining informed consent is a dynamic process building on trusting relationships. It should include open and honest discussions about benefits and risks. Investigators may benefit from training in effective communication. Finally, involving parents in neonatal research including the development of the informed consent form and the process of obtaining consent should be considered standard practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.