Evidence map›Paper›PMID 33437655›Full record

ArticleToxicology reports2021

Safety assessment of a novel thermostable phytase.

Jana Nováková, Adél Vértesi, Erzsébet Béres, Spas Petkov, Katherine E Niederberger, Davy Van Gaver, Gábor Hirka, Zoltán Balázs

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jana NovákováMediTox s.r.o., Pod Zamkem 279, 281 25, Konarovice, Czech Republic.
Adél VértesiToxi-COOP Toxicological Research Center ZRT., Balatonfüred, Arácsi út 97, 8230, Hungary.
Erzsébet BéresToxi-COOP Toxicological Research Center ZRT., Balatonfüred, Arácsi út 97, 8230, Hungary.
Spas PetkovHuvepharma EOOD, 39 Petar Rakov Street, 4550, Peshtera, Bulgaria.
Katherine E NiederbergerLeveret GmbH, Aberenrain 30, 6340, Baar, Switzerland.
Davy Van GaverHuvepharma N.V., Uitbreidingstraat 80, 2600, Antwerp, Belgium.
Gábor HirkaToxi-COOP Toxicological Research Center ZRT., Balatonfüred, Arácsi út 97, 8230, Hungary.
Zoltán BalázsLeveret GmbH, Aberenrain 30, 6340, Baar, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel 6-phytase (Phytase TSP, trade name OptiPhos® PLUS) with improved thermostability has been developed for use in animal feed. The safety of the new phytase was evaluated by testing for genotoxicity and subchronic toxicity. In

Indexed as

2AA, 2-aminoanthracene6-phytase9AA, 9-aminoacridineAAFCO, Association of American Feed Control OfficialsANOVA, analysis of variancebw, body weightDMSO, Dimethyl sulfoxideGenotoxicityGLP, Good Laboratory PracticeIACUC, Institutional Animal Care and Use CommitteeMMS, methylmethanesulfonateMPCE, polychromatic erythrocytes with micronucleiNOAEL, no observed adverse effect levelNPD, 4-nitro-12-phenylenediamineOECD, Organisation for Economic Co-OperationOptiPhos PLUSPCE, polychromatic erythrocytePhytase TSPSAZ, sodium azideSubchronic toxicityThermostable phytaseToxicity

Identifiers

PMID33437655
PMCPMC7787994

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.