Evidence map›Paper›PMID 33437653›Full record

ArticleToxicology reports2021

Toxicity of colloidal silver products and their marketing claims in Finland.

Veera Leino, Riikka Airaksinen, Matti Viluksela, Kirsi Vähäkangas

Abstract read
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Veera LeinoSchool of Pharmacy/Toxicology, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Riikka AiraksinenFinnish Institute for Health and Welfare, Kuopio, Finland.
Matti VilukselaSchool of Pharmacy/Toxicology, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.
Kirsi VähäkangasSchool of Pharmacy/Toxicology, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe aim was to investigate the marketing practices, beliefs and health claims regarding the use of colloidal silver in Finland. Silver nanoparticles (AgNPs) are potentially toxic due to their small size and Ag

methodsContents of three company websites selling colloidal silver were reviewed, and the claims used in the marketing of colloidal silver were compared to the scientific information about silver. In Facebook posts and discussion about colloidal silver were analyzed.

resultsIn Finland, the marketing of colloidal silver products on websites selling the products did not follow the regulations of authorities; several scientifically unfounded claims about the efficacy and medical use of colloidal silver were found. After the Finnish Broadcasting Company (Yle) documentary and an intervention by authorities, contents of the websites were changed, but still questionable information and misleading claims could be found. In the analyzed Facebook groups attitudes towards medical use of colloidal silver were uncritically positive, internal use was highly promoted and the restrictions of use were considered unjustified.

conclusionsThe use of quackery products such as colloidal silver can be dangerous, and their use and marketing should be controlled and restricted.

Indexed as

AgNPs, silver nanoparticlesAPTT, active partial thromboplastin timeATP, adenosine triphosphateColloidal silverEvira, the finnish food safety authorityFimea, the finnish medicines agencyLDH, lactate dehydrogenaseNOAEL, no observable adverse effect levelPseudo-medicineQuackeryRfD, reference doseROS, reactive oxygen speciesSilver nanoparticlesSocial mediaTHL, the finnish institute for health and welfareTukes, the finnish safety and chemicals agencyU.S. EPA, the environmental protection agency of the USAWeb-based advertisingWHO, the World Health OrganizationYle, the finnish broadcasting company

Identifiers

PMID33437653
PMCPMC7786010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.